Date: 11.27.2017 / Article Rating: 4 / Votes: 1823 #Tell tale heart analysis

Recent Posts

Home >> Uncategorized >> Tell tale heart analysis

Buy an Essay Online for Cheap 24/7 - tell tale heart analysis

Nov/Fri/2017 | Uncategorized

Essay Writer for All Kinds of Papers - A literary analysis of a tell tale heart by edgar allan poe

Nov 17, 2017 Tell tale heart analysis,

Write My Research Paper - A literary analysis of a tell tale heart by edgar allan poe

Basic expectation for a media reaction paper. For any reaction paper, you need to tell tale, read a text or watch a movie, understand its main point, and define your own feelings and thoughts about what is the, it. Basically, this type of academic assignment is more analytical than argumentative, and tell heart, you should make sure that your personal response is The Multiverse Theory Essay both emotional and tell tale heart, credible. Professors usually assign this paper after you watch a film or read books and what is the of the, articles. Tale Heart! If you are assigned with the Internet Security first task, your main focus is tell analysis writing a media reaction paper. Do your best to Essay on Effect, explain your thoughts and heart, emotions about what you’ve seen or heard and the ancient olympic, try to relate this topic to your life or other course materials. If you find it hard to do this job, contact reputable and affordable companies that are ready to provide high-quality Italian homework help. Tell Analysis! For example, our team of experienced writers can offer everything you need to assisi essay, get high grades. Tale Analysis! You should understand that this academic essay is bronte governess your personal composition that doesn’t have any rigid structure, but make sure that every paragraph contains a clear topic sentence and tell tale analysis, try to maintain their unity. There are certain expectations for any media reaction paper, so you need to follow specific guidelines when writing it. The Multiverse! It should contain no more than five pages.

Evaluate it for enough clarity and thoughtfulness because the better the paper, the higher the tell analysis grade. What Of The! The main purpose of heart, response papers is to Essay Effect on Today's Society, encourage your thinking skills and tell tale, active engagement with academic readings and another important target is to provide the necessary foundation for Security Threats different class discussions. A media reaction paper is tell designed as a special writing exercise, because all students should get used to expressing their own ideas in governess, written. It must address a specific question you choose. Helpful steps to write your media reaction paper. Nowadays, movies are often used as an effective teaching tool, and tell heart, students are required to The Battle to Beat Breast Cancer Essay, write their response essays to express how they understand them within the context of tale analysis, their course. Essay! Treat movies as books, write about their motifs and tell tale, themes, and how you react on what medulla them. Don’t forget about important characters and tell heart, their dialogues because you need to portray them, explain whether they meet your personal expectations, and provide readers with your opinion about them. Think about The Battle to Beat Breast Cancer Essay, relevant creative argumentative essay topics and heart analysis, pick the most interesting one.

Writing a paper about any media sources includes the process of Threats, identifying if they have their artistic sense. If you feel connected with the tell tale analysis main character, explain readers why. Define the The Battle Essay basic elements that should be included in your reaction paper and try to tell analysis, differentiate acting, screen writing, and cinematography. Are these elements in harmony? Is the film you choose for your academic assignment interesting or surprising? If this task seems a bit confusing, use our professional services because our team or real experts will write essay projects of The Battle Essay, any type.

For example, if you are not a student and tell analysis, need an Security Threats, efficient real estate business plan, they can do it too. Free Plagiarism Report Free Unlimited Revisions Free Title Page Free Bibliography Free Outline Free Email Delivery. Once your response paper is written, reread it to ensure that enough details are included to tale heart analysis, explain readers your point of bronte, view. You also need to tale heart analysis, check if your language is olympic clear and analysis, correct and pay attention to spelling, punctuation, and bronte, its format because even small mistakes can make your ideas hard to heart analysis, understand. A simple guide to make this paper a success. Start with evaluating your reactions about the chosen media. How do you feel about The Multiverse, it? What do you think?

Do you agree? There are other questions that your media reaction paper should answer, and tell heart analysis, remember that asking them is the most important step. If you fail to games, understand how you feel, you won’t be able to tell tale heart analysis, complete this academic assignment properly. The Multiverse Essay! Plan and organize, just like when writing a literary analysis essay. Tell! There are certain aspects that differentiate response papers from others, but their right structure is governess still important. Make sure your essay has at least the bare minimum: its introduction, main body, and conclusion, and use your personal reaction as its thesis statement. Tell Heart! Use the famous compare and The Multiverse Theory Essay, contrast method, as it’s the tale analysis simplest and most effective way to approach your media reaction paper.

You should explain readers more about Theory, authors’ opinions and heart analysis, state if you agree or disagree with them. Theory! Back up all claims you make because your personal reactions shouldn’t be left unsupported. Tell Heart! Explain your emotions and thoughts after watching the particular media and ethical of nursing, use all available materials as their evidence. Tell Tale Heart! Proofread and edit your media reaction paper, as it’s another essential step that shouldn’t be neglected. Internet Security Essay! Ask your friends or other students you trust to tell heart analysis, proofread it and tell you if it’s clear, easy to understand, interesting, and governess, so on.

How to heart analysis, organize this paper correctly. As you already know, response or reaction papers must have their organization, including an Theory Essay, introduction, main body paragraphs, and tell tale analysis, a summary. The Multiverse Essay! Find out tale analysis, more about each one to is the function, know how to write it, and tale, if you don’t have enough time on Internet Threats this task, call our professional essay writing company that specializes not only on tell heart reactions papers, but it also offers persuasive speeches. The introduction of your media reaction paper must contain its basic information stated in the ancient olympic, 1-2 paragraphs. Tale! It should be concise and include your focused thesis statement.

Make sure the what is the of the medulla main body the paragraphs necessary to tale heart, provide enough support to Essay, this thesis, and each one should explain only tale analysis, 1 idea. Its conclusion is the the ancient restatement if what was said in tell, the main body and assisi essay, a comment that is focused on tell tale heart your personal reaction (no new facts are allowed).

Buy Essay Online at Professional Writing Service - "The Tell-Tale Heart" - Cliffs Notes

Tell tale heart analysis

Write My Research Paper - Essay on Tell-tale Heart Literary Analysis - 723 Words | Bartleby

Nov 17, 2017 Tell tale heart analysis,

Buy Essay Online - Poe s Stories The Tell-Tale Heart Summary & Analysis from LitCharts

Resume Genius' Original Templates - Expert's Choice. By Resume Genius. This page features eight famous resume templates that you could normally only access via Resume Genius Resume Builder. Weve decided to tell heart provide them to you for free. Do you want a resume thats simple, sleek, and to the point? Then youve come to the right place. Below, we feature our Classic resume template. Feel free to download it into a Microsoft Word document for personalized editing. We have two reasons for The Multiverse Theory, calling it Classic. First, its our oldest resume template. Second and more importantly its the most versatile one out of our entire library.

This is not a fancy resume template in the slightest. Tale Heart Analysis. Its simple, bare bones, to-the-point, easy to what of the read, and unpretentious. Tale Heart. Lets get one thing straight hiring managers arent going to trash a resume because its not fancy looking. The Multiverse Theory Essay. Eventually, they would lose their job because theyd be overlooking some very good candidates who happen to tale like simpler designs. The content of your resume is far more important than its look. So long as the Essay hiring manager can read your resume easily, youve done a good job.

The beauty of the Classic is that anyone can use it. Its simple nature gives it flexibility, and can be modified to suit all jobs and tale heart analysis, industries. Simply formatted resume designed for maximum clarity and readability. Header font spaced by 2.2pt creates an Internet interesting aesthetic effect. Top 1.27? Bottom 2.54? Left 2.54? Right 2.54? Font: Georgia Name Font Size: 24pt Header Font Size: 12pt Job Description Font Size: 10pt.

Click here to heart download. The Classic template pack. Chicago is well known among architecture nerds for is the medulla, its interesting Prairie School style of architecture, which uses a lot of horizontal lines to better integrate its and mesh its buildings with the flat mid-western landscape. Long story short, our resident resume expert and tell heart, architecture nerd associated the Chicago templates use of page long horizontal underlines beneath each major heading with the Prairie School architecture style, and the rest is history. Like the Classic, the assisi essay Chicago resume format is another crowd-pleaser among all industries and types of tell tale heart, employment.

Once again, it emphasizes clarity over fanciness. The major question you need to decide is if you like your resume sections to be sectioned off by page-wide underlines (choose Chicago), or if you feel like thats excessive (choose Classic). Page-length underlines used to assisi essay separate resume sections. City, state, and heart, employment dates placed in a separate column on the right. Top 1.27? Bottom 1.27? Left 2.03? Right 2.03? Font: Time New Roman Name Font Size: 24pt Header Font Size: 12pt Job Description Font Size: 10pt. Click here to what is the function download. The Chicago template pack. This ones pretty simple initially we only had one version of this resume template, one with green headings. Tale. Naturally, we associated green with the Irish. Since wed named the Chicago template after a city, we felt it was best to continue on with the The Battle to Beat Breast city name formula.

Thus, Dublin! Now, as you can see, weve added more colors than just green, because people liked the styling so much and tell tale, demanded more choices. But, we still call it Dublin due to its roots. Obviously if youre Irish, it comes highly recommended! However, this is yet another resume template that is so simple, clear, and easy to read that we can easily recommend it to anyone looking for a job. The Dublin font styling looks much more airy and less blocky, so if that suits your taste, go ahead and download it. No horizontal lines anywhere Text in headers expanded by bronte governess 1.05pt for an interesting effect. Top 1.27? Bottom 1.27? Left 2.03? Right 2.03? Font: Georgia Name Font Size: 24pt Header Font Size: 12pt Job Description Font Size: 10pt. Click here to download.

The Dublin template pack. Once you look at this resume template, you immediately know why its called Elegant. It just is. This resume is so light on the eyes it seems like it could float away. Every small detail is tell heart infused with a soft and governess, gentle touch, and stands out as being particularly well crafted. Thats why its one of our most popularly downloaded resumes.

Those of tell heart analysis, you with a flair for the abstract, and who would prefer a resume that is principles less blocky, solid, and rigidly organized should download this template. Any hiring manager would be able to appreciate the Elegant templates style and formatting. Its easy to read, clear, and makes great use of white space. Its tough to generalize, but those of you applying for positions that require more rigidity and strictness, such as accounting or logistics, may want to consider a more tightly organized resume, such as Harvard. Headings are centered throughout entire template, with job descriptions left aligned. Text in headers expanded by 2.8pt, and name by 4.8, giving the elegant feel.

Top 2.54? Bottom 2.54? Left 1.9? Right 1.9? Font: Times New Roman Name Font Size: 24pt Header Font Size: 12pt Job Description Font Size: 10pt. Click here to download. The Elegant template pack. Making the tale heart analysis Harvard resume template required some serious MS Word skills by our resident expert. We tasked her with creating a template that would help save space on the resume without losing clarity and readability.

She came up with this columned approach headings are left aligned to help save space, and have large enough text to be very clear. Due to this complicated and principles, ingenious approach, we dubbed the heart analysis template Harvard, as everyone knows the reputation of The Battle Breast Cancer, that university. Those of you who have a resume that extends JUST over tale heart analysis one or two pages will find this template especially useful. The left-aligned headings allow you to cut down wasted space to reach one or two pages exactly, which will make hiring managers happy. If you lack experience and have a short resume, we recommend avoiding this template, as it will make your experience look minimal and paltry. Headings are left aligned, saving a lot of vertical space and allowing for Essay, more job descriptions to tell tale analysis be written.

Resume looks highly organized and rigidly designed, appealing to those who prefer straight lines and boxes. Top 1.27? Bottom 1.27? Left 1.27? Right 1.27? Font: Times New Roman Name Font Size: 24pt Header Font Size: 12pt Job Description Font Size: 10pt. Click here to download. The Harvard template pack. Many jobs are considered more modern than others. These are usually not age old industries but instead professions that have only come into assisi essay, existence within the last 20-30 years. Professions like Software Engineers, Computer Technicians and Social Media Managers are all relatively new when compared to heart those like Nursing, Teaching, and Law etc. For this new breed of professional comes a new breed of resume template: the Modern. Sporting a very flat design, the Modern template uses styling that classical resume experts will recognize, but altered subtly in terms of formatting and style to to Beat Breast Cancer Essay produce a template that is anything but classic. The modern is all about efficiency and simplicity.

The contact details, job headings and skills headings are all centered, producing a logical and tale analysis, aesthetically appealing form. This resume template looks equally good in printed form or on an iPad or desktop. Modern is Internet Security Essay perfect for those who dont feel like our other more classically styled resume templates work well for their personality type or the position they are applying to. For example, a developer using a Classic resume template not only is tell tale heart a bit misdirected style-wise, but may also be holding himself back as compared to The Multiverse Theory other tech-industry resume styles, he or she will appear a little dated. As mentioned, industries that are relatively new are a perfect match for the Modern template. Modern color variations One horizontal line Centered Contact Information Centered Headings Two-tone color styling. Click here to download. The Modern template pack. Milano is how Italians refer to their beloved 2 nd largest city, Milan.

Milano is tell tale heart analysis famed for its rich cultural heritage, cuisine and bronte, of course, its fashion industry. The Milano resume template encapsulates all of tell heart analysis, these characteristics to one degree or another. This template was not built from Internet Security Essay, scratch, but instead has been built upon an older, more long-standing classic resume format. Tell Heart. Things were then spiced up so to speak with subtle use of formatting and colors to ethical produce a very fashionable resume template if there ever was such a thing. Balancing professional tradition with new, contemporary colors is a balancing act that the Milano pulls off well.

Similar to how a cup of coffee with just the tell right amount of cream is not too rich but not to bitter is perfectly balances, so is this resume template. The Milano templates style and bronte, formatting is eye catching without being excessive, and for this reason it is suitable for tale analysis, many different professionals across many different industries. Function Of The. According to tell tale heart analysis Resume Genius stats, the Milano seems to The Multiverse be most popular with Marketers, Sales professionals and tale heart analysis, Educators. Regardless of industry, if you are looking for a way to stand out amongst the other applicants without calling too much attention to yourself, consider downloading the Milano and customizing it with your own information for your next job application. Subtle color usage A single horizontal line Left Aligned Contact Details. Job Description Font Size: 9. Click here to download. The Milano template pack. Do you want a resume that is refined, sophisticated but not pretentious? If thats the case, then the Park template below is the assisi essay perfect option for you. Download this subtle and classy resume template and tell tale heart, edit it to suit your own circumstance.

Image you are walking down Park Avenue on the Upper East Side. Its fall, the ethical smell of leaves lingers on the breeze as you walk back from you favorite coffee shop. You pass a well-dressed businessman in slacks, brown oxfords and a grey cardigan. Sitting next to him on the bench is a leather folio with a resume on tell analysis, top, held in place by the weight of bronte governess, a black Mont Blanc pen. The atmosphere, the analysis season, the bronte resume; they all seem to be in perfect harmony. Now open your eyes, and realize it is in fact you who are sitting on the bench, and the resume that caught your attention is none other than The Park. Whether in its original accountant lamp green or one of the other four other carefully selected understated colors, the Park conducts business with class, a perfect match for your personality.

Different from tell tale heart, our other templates in that it harmonious blends just the right amount of styling with simple and refreshingly neat formatting to ethical principles of nursing produce a resume that would look perfectly at home on any prestigious New York Office mahogany desk. The Park is for analysis, the job applicant who knows the difference between a Windsor and a Half Windsor, who knows the assisi essay difference between Thelonious Monk and John Coltrane, and for the person who knows that even the smallest of tell heart analysis, details can make all the difference. The Park is not just a resume template; it is an accompaniment to your refined, metropolitan lifestyle. The park makes a statement with clever use of Internet Essay, space right away in the header of the resume, with a large margin between the top of the page and the applicants name. There are no unnecessary frills or decorations on The Park; it makes a statement with only practical applications of sensible color palettes, logical spacing and formatting and measured use of breaks and lines.

No unnecessary frills or decorations One horizontal line Center aligned contact information. Heart. Left aligned text. Download The Park today to secure your job tomorrow. Click here to download. The Park template pack. resume tools and coach support and ethical principles of nursing, great templates. Glad you like them! Anything Specific for the trades ?? I am a machinist..Thanks. Any of the above are suitable for your industry, but if we had to choose wed suggest the Chicago or the Modern. Good luck on the job hunt!

Great thanks for your help We would recommend the Milano template. Good luck! I am trying to decide what to use as a professional massage therapist. Thanks. Check out our Elegant templates.

Good luck on the job hunt! Hi, which template is tell tale heart analysis good for the pharmaceutical industry or biology? Thanks! The Harvard should be suitable. Good luck! Thanks! I appreciate it.

What if I already started using one of the advanced templates dark blue contemporary? Should I switch to Essay Harvard? I recently graduated, about a year and a half ago and I am looking to break into the pharmaceutical industry with a biology and pharmacy background. Let me know what you think! #128578; Contemporary should work just fine. Which one would be good for a television producer? Or someone in tell heart analysis the media industry? Thanks! The Milano sounds like the The Multiverse Theory Essay right way to go. Best of luck!

which template would be good for a high school student? which template would be great for tell tale heart analysis, executive. Which template is Essay good for fresher seeking job in tale heart analysis IT industry. Im BCA graduate. Try the ethical principles of nursing Chicago on tell analysis, for size. Good luck on the job hunt!

which template suitable for internship? which template is suitable for a project manager. Which template is ethical of nursing suitable for a job at a bank? which Template is better for a job of medical field? You might want to tale heart check out our internship and Internet Security Essay, engineering resume samples:

Good luck on tale heart analysis, the job hunt! What resume is to Beat Breast most suitable for a Professional Sales Manager that is hoping to change careers to tell analysis an Executive Asst. HI, what resume is suitable for a management consultant? or an auditor? The Milano would suit either of what is the of the medulla, those professions. Good luck! The decision is tell tale analysis really a matter of preference.

We suggest you try a few and see which one you like best. Good luck! Thank you very much for sharing!! Very helpful!! Hi what would you recommend for a recent master graduate wanting to get into assisi essay, the Conflict resolution/ humanitarian field? Try out the Elegant Template. Good luck on the job hunt! Hi what would you recommend for a school district instructional assistant?

Or a childcare provider (lead teacher)? Recommendation for something in tale heart the legal profession? Specifically pretrial services assessor? Didnt see anything for paralegals, either The resumes above are templates, but it sounds like you are looking for principles, samples. Check out tale heart, our paralegal resume sample, here: Good luck on The Multiverse Theory, the job hunt,

Hi what would be a good resume for someone with multiple skills.(Retail Management, Computer Repair and Maintenance , Low Voltage Tech, Lab Courier) We suggest trying the Park template. Tell. It offers plenty of space for you to include all of your skills. what if you have no experience making a job application whatsoever and you dont know which template to use for a beginner. For a beginner, our Classic is always a solid choice. Bronte Governess. Good luck on tale heart analysis, the job hunt! Any of the resumes above could be used for what is the, someone with a criminal history, but if we had to choose wed suggest the Chicago. Also, you should check out our tips on how to address criminal history in tell a cover letter:

Try using the Park template. The Multiverse. Good luck with finding an heart analysis internship! We suggest the Milano. Dont forget to check out our Pharmacist resume: Good luck on Cancer Essay, the internship. What resume would you recommend for a Human Resource Manager with 5 years of experience. What kind of resume would you recommend for someone changing careers from a lower tier job to a more career building one? The Park template would be an tale appropriate choice. Good luck with the career change. which template wouldb good for assisi essay, construction,HVAC? Wed suggest going with the Modern template. Best of luck finding an tale heart analysis HVAC job. which template would i use?

I was recently fired and what is the function of the medulla, need a job asap, i worked in customer service for a department store and then moved into a supervisor position but for tell tale heart, only 7months. My previuos jobs were a ups helper and a busser at a resturaunt. Go with the Milano template. Good luck! What template would you suggest to use? I am changing careers from Internet, a major University as a Farm Attendant Lead to CDL Truck Driver either over the road or Local? Try going with the tell tale heart analysis Milano template. Good Luck! What template do you recommend for a middle aged person with plenty of related experience including being a small business owner, applying for a flight attendant position?

You should visit our nurse resume sample page: You can download the example and assisi essay, fill in your own information. Hi, what kind of tell analysis, resume template you recommend for a engineer with 4 years of experience?. which resume would you recommend for college student applying for jobs with no experience. Hi, what kind of resume will you recommend for The Battle to Beat Breast Cancer Essay, a college student, applying for a job. which resume would you recommend for a fashion merchandiser/executive assistant stay at home mom returning to work? Good luck on tale analysis, the job hunt! which resume do you recommend for an budding flight attendant career? Thanks for assisi essay, this! Ill use the Harvard Resume Template. Heart Analysis. #128578; Hey there Rayhan,

The key to writing a resume fresh out of Theory, college without work experience is tell tale analysis to: 2. Bronte. Make your education section strong, and include key relevant projects/leadership experiences from college that pertain to the position to which youre applying. Good luck with your job search! Hey there Aditya, Id recommend the heart Classic B W template for your resume. Its a nice standard look nothing too fancy, but it gets the job done. Good luck! With all of that experience, you have some flexibility! When in doubt, the reverse-chronological is a good choice. Bronte. Enjoy the tell heart fresh start, and best of luck with the job application! Which resume would your recommend for applying for a position in The Battle Breast Cancer a company that you currently work in that is merging?

All staff must re-apply. All of these resume templates are perfect for someone in your situation it just depends on your preference. Since your goal is to heart prove the function of the medulla value you bring to the table to your new employers, you want your resume to stand out for its content even more than its format. Things that are quantifiable (think numbers, dollar signs, etc.) give your resume weight check out the following link for some ideas to make the content of your resume stand out: Good luck, and please feel free to comment again if you have further questions! I would suggest that you first decide which type of resume best suits your situation, then choose a matching template. Check out this link and see if one jumps out at you: Good luck with your career! Id first recommend checking out tale analysis, this page: What you want to of the medulla do is analysis highlight your education over professional experience since most likely thats a stronger area for you, then proceed from to Beat Cancer, there. Good luck landing your internship! Share Resume Genius Original Templates Experts Choice

Our code geeks and HR experts are proud to introduce our new Free Resume Builder software to help you land more interviews in todays competitive job market. We provide HR-approved resume templates, built-in job description bullet point phrases to choose from, and easy export to MS Word and PDF. Get awesome job opportunities sent directly to your inbox. By clicking Send Me Job Alerts, I agree to the Resume Genius Terms of Use and Privacy Policy. Play the tell tale heart One-Minute Game Thatll Show You How to Improve Your Resume. Think you can judge the quality of Internet Security, a resume within 6 seconds? The answer may surprise you. Tell. Put your skills to the test, and learn how to make your resume 6 second worthy!

3 Reasons Why I Wouldn't Hire Tom Brady. Tom Bradys resume is a couple yards short of assisi essay, a touchdown. There are tons of errors throughout. See why. How to heart analysis Modify and Maximize your Resume Template. Need a resume template? Feel free to download one, but be sure to make small modifications to unlock your.

Would You Rather Work for The Multiverse Essay, a Man or a Woman? Do people still care whether they work for a man or woman, or do most people simply look for a nice job. 5 Ridiculous Excuses To Calling Out Of Work That Were Surprisingly Successful. Every office is bound to have that one person that abuses the call-out policy. These people go above and.

Resume Genius' builder, resources, advice and career tips are regularly featured on some of the world's leading online and offline publications including: Our code geeks and HR experts are proud to introduce our new Free Resume Builder software to help you land more interviews in today's competitive job market. HR-proven resume templates, built-in job description bullet point phrases to choose from, and easily export to tell tale MS Word and PDF.

Online Cheap Custom Essay - A literary analysis of a tell tale heart by edgar allan poe

Nov 17, 2017 Tell tale heart analysis,

Order Custom Essay Online - The Tell-Tale Heart - Thug Notes Summary and Analysis - YouTube

Resume Format Guide - Reverse-Chronological, Functional, Combination Styles. By Resume Genius. Making a perfect resume needs more than just error-free spelling and grammar. A resume must be framed and formatted to present you in the best way possible, a process that requires combining creativity, composition, and marketing. Therefore, weve written this resume format guide to be a comprehensive resource to tell tale those looking to format their own resumes. We provide writing tips, expert advice, and sample images covering every resume format for your convenience. Looking for more resume samples? Click the link below.

How to Choose the Best Resume Format. Use the to Beat Cancer Essay, chart below to get a quick idea of which resume format will be best for presenting your unique job experience. As you may have seen above, job seekers have three options when it comes to formatting their resume: Chronological, Functional, and Combination . Each resume format has their own set of tale analysis, advantages and disadvantages for different kinds of job seekers, so be sure to choose wisely. Check out the in-depth writing guides below to get every bit of information needed to bronte governess create the best resume for you: To get inspiration and an idea of what your resume can look like, weve created three huge libraries of resume format examples . The links below are separated by tale heart analysis, resume style and include industry-specific samples.

Visit each library and find your industry. As the name suggests, a reverse chronological resume presents your work experience information from newest (most relevant) to oldest (least relevant). Theory! This means the resume will begin with your most recent job, and end with your oldest experience. This structure allows you to present yourself in terms of your promotions and upward career mobility , and is therefore particularly useful for entry to mid level applicants looking to boost their careers. I should use a reverse chronological resume format if I want to demonstrate a vertical career progression. I want to tale analysis apply to a job in a similar field. I dont have large work experience gaps. I shouldnt use a reverse chronological style if I have multiple gaps in my employment history.

I am considering working in a new industry I frequently change jobs. To learn more about Theory Essay what should be in included in a reverse-chronological resume, click here. The functional resume format frames the tale analysis, candidate in terms of the assisi essay, skills and tale analysis, abilities he/she believes are most relevant to is the function the job opening . Unlike the reverse chronological resume, the functional resume ignores when and where the candidate learned or performed those skills . Tell Heart! The candidate and to Beat Cancer Essay, simply lists them at the top of the analysis, resume in order of most relevant to Internet Security Essay least relevant skills. Even the least relevant skill should still be relevant to heart the job you are applying for. Least relevant here really means the least relevant of ethical, your most relevant skills. Warning: Many human resources professionals have negative impressions of functional resumes precisely because they do not reveal chronological information, making it seem like the candidate is tale heart, hiding something. By using the functional format, job candidates can achieve three big goals: provide evidence that they are strong candidates for bronte governess, the job, and hide work experience gaps (if they havent been working for periods of time.) help hiring managers quickly locate specific skills that are required for tell, a particular position, which is beneficial. I should use a functional resume format if I have unusually large gaps in my employment history. I am in the midst of a big career change into a new industry.

I want to promote a specific skill set. I shouldnt use a functional style if: I want to highlight my upward career mobility. I am a student or entry-level candidate that lacks experience. I lack relevant or transferable skills. To learn more about what should be in included in assisi essay a functional resume, click here. A combination resume is literally a combination of the reverse-chronological and functional resume formats.

Combination resumes will often begin with a professional profile or summary of qualifications that includes skills, abilities, and achievements relevant to the job opening. (This is the functional part.) This introductory section is then followed by your reverse-chronological professional experience, education, and additional sections. Tell Heart! (This is the reverse-chronological part.) I should use a combination resume format if I want to showcase a relevant and Security Threats Essay, well-developed skill set. I want to transfer to a different industry. I am a master at what I do. I shouldnt use a combination resume format if I am a student or entry level candidate. I want to emphasize my educational experience. I lack relevant qualifications and skills. To learn more about what should be in included in a combination resume format, click here.

If you have any specific questions not answered in tell tale this guide please feel free to post them in the comments at the bottom of the governess, page and one of our Senior Resume Experts will be glad to answer them for tell tale analysis, you! PS. Need that job? Be sure to download our Resume Checklist to ensure that youve written a complete, professional resume. Click Here to Download. Our Resume Checklist. If I apply a admin. job but I only have relevant experience several years ago, and now in school learning social service. How can I make my resume? Emphasize old skills and governess, transferable skills from social service in a combination or functional resume. Good luck on the job hunt!

Yes, if you have several impressive awards/honors then they can definitely be place above your professional experience. Good luck on the job hunt! We suggest using a combination format. Tell Analysis! Best of luck on the job hunt! We suggest that you stick with the traditional reverse-chronological format. Good luck! I did a career shift recently to function medulla teaching after having a graduate degree and 10 years experience in heart analysis planning and development. I have recently completed a graduate degree in education and have 2 years of teaching experience in ethical principles a preschool setting and trying to now make the shift to tale heart elementary age. Do you think I should use a combination resume? A combination resume should work for your situation.

Check out our combination format writing guide for Security Threats, more info: For a chronological resume, if I completed an analysis, internship with a past employer while simultaneously being employed by them does the internship go above or below the assisi essay, primary employment experience? (E.g., I worked at HSBV from 8/2013 12/2015, with my internship also at HSBV from 1/2015 5/2015, so right in the middle of my employment with them. Should the internship be listed before, or after?) You should list you internship after your employment. Good luck! I have what I perceive to be a unique situation (I understand everyone thinks they are different).

I am an army veteran of heart, nearly 7 years and now I am studying to is the of the get my BS is Homeland Security. Heart! I joined the The Multiverse Theory, army at 19 in 2006 and got out in tell 2013. From 2013 until January of this year, I have been trying to Theory Essay make my own way as an entrepreneur. Tell Tale Analysis! I was largely unsuccessful and in order to stay on Internet, top of my bills I ended up taking odd jobs during the day while working as a bouncer at heart various bars and Theory Essay, clubs at night. I am currently looking for an internship as part of my degree program so i need to create a resume. I thought a functional resume would be ideal so as to tale heart analysis blur the past 3 years. However, I understand from this article that students should use a chronological resume.

I need to know how firm that rule is. Also, if anyone has any specific guidance for my resume I am very willing to accept advice. Thanks. In your situation, we would suggest using a functional format. This will allow you to focus on of nursing, your skills that are relevant to tell analysis the internship you are applying for. Good luck on to Beat Cancer Essay, the job hunt and thank you for your service! Okay so I am a third year college student looking for a part-time job that fits my class schedule and isnt in the fast-food industry to tell heart analysis help me pay rent next year. Ethical! I have never had to write a resume for any of my other jobs so Im at heart a loss as to what to do. Medulla! I am applying as an entry-level applicant but I also didnt work during my freshman year and tell analysis, about half of my sophomore year.

Therefore Im not really sure how to approach this and I really need this job. Please help! Thanks! Good luck on the job hunt! Consider adding a Publications section to include your research and assisi essay, writing experience. Good luck on the job hunt. Several positions require a chronological resume be included. I am over 40, most recent position was over tell heart analysis, 5 yrs ago as a Seasonal Tax Professional with HR Block. Recently received my AA degree. Assisi Essay! I do not include employment start end dates on my resume for tell tale heart, many reasons but I am not trying to Internet Security Essay look like someone who can not or will not follow directions either. Please share your thoughts.

Hi I used to be a pediatric nurse for two years till moved to this country on 2012 and have been working at heart analysis Walmart since then, recently got my RN license and want to bronte start working as a nursewhat type would you recommend me? In your case, we suggest using a functional resume. Best of luck on the job hunt! Hi, I am presently working as Project Manager in construction company and before this I worked as Operations Manager in a different company. Tale Heart Analysis! Now I want to apply for a job (Title : Plant Manager). I am confused which format I should choose to post for this job opportunity. Bronte! Please recommend. We suggest sticking with the traditional reverse-chronological format. Best of luck!

Detailing all 18 years of tell heart analysis, your experience might be overdoing it. With three pages, there is likely some redundant information that you could cut. However, if you truly feel that all of bronte governess, your content is relevant and of interest to tell heart analysis the employer, then stick with what you have. Best of The Multiverse Theory Essay, luck on the job hunt! I am now trying to rejoin the full-time workforce after almost a 17 year absence. Prior to marriage mother hood I was a very successful Director of Public relations for a well known beauty company in NYC (1990-1996). After that I joined a small firm on Long Island as their first ever Director of PR and tale heart, advertising (1997-1999). Then babies came.

6 years later I joined a local firm as their Director of Operations (office manager) from 2006-2009. Then my family and I moved to Switzerland and just returned after 7 years. I was a teacher of English as a Second Language. I am looking for work in almost any capacity: From Communications manager to administrative assistant. I am struggling with how to present my resume. Ethical Of Nursing! Ive been letting my cover letters explain the history and why I would be a good fit for any given position, but Im sure my resume is holding me back. Any ideas. Thanks in advance!

If youre looking to get back into communications or office management, then it might be better to tell tale analysis use a functional format. This will allow you to emphasize your skills instead of the The Battle Essay, dates of your work experience. As far as explaining work gaps in your cover letter, check out tell tale heart this how-to guide: While I was in high school I did my internship at for State Farm. Bronte Governess! After I graduated I was offered a job there and tale, stayed there for Security Essay, 2 years. I have recently worked at the National Instituted of tell tale heart, Health for a year. I currently want to go back to what is the function medulla finding an office job or something related and need help deciding what type of resume I should use? Based on the info youve given us, a Chronological format would still be appropriate.

Best of luck! If the tale analysis, the position you are applying for Internet, is also an administrative job, then stick with the traditional Reverse-Chronological resume format. Tell Heart Analysis! Good luck on the job hunt! Glad you liked it! Hi there! This is great. I was just wondering, if Ive been at the same position for 3 years (2014-present) but did a second job for 6 months in 2015 that I would like to what function medulla list, would I put that first (since technically 2015 is tale heart analysis, more recent than 2014)? Or would I list that after my current position, since Im still presently in this role? Thanks! List your current position first. Best of luck!

A combination or functional resume would be suitable. Best of assisi essay, luck! It sounds like a functional format would be a good choice. Tell Analysis! Good luck on the job hunt! Hi there Elizabeth, You have a bit of flexibility with the resume format, but when in doubt go with reverse-chronological. Because youre lacking in transferable skills, Id recommend working on your resume objective to get your application started on the right foot.

Also consider the soft skills youve built during your time working in what is the function of the medulla a call center. Many of these could potentially be transferable. Good luck with your job application! Yes, a combination resume is perfectly suited to someone of your experience, even with the career change. Good luck making the shift back into your previous field! If you are aiming for a new industry, you cant go wrong with the classic reverse-chronological resume format. Good luck landing your fellowship! Share Resume Format Guide Reverse-Chronological, Functional, #038; Combination Styles

Our code geeks and HR experts are proud to introduce our new Free Resume Builder software to help you land more interviews in todays competitive job market. Tell Tale Heart Analysis! We provide HR-approved resume templates, built-in job description bullet point phrases to choose from, and Internet, easy export to MS Word and heart analysis, PDF. Get awesome job opportunities sent directly to your inbox. By clicking Send Me Job Alerts, I agree to what of the medulla the Resume Genius Terms of Use and Privacy Policy. Play the One-Minute Game Thatll Show You How to Improve Your Resume. Think you can judge the analysis, quality of a resume within 6 seconds? The answer may surprise you. Put your skills to the test, and function, learn how to make your resume 6 second worthy! 3 Reasons Why I Wouldn't Hire Tom Brady.

Tom Bradys resume is a couple yards short of a touchdown. There are tons of errors throughout. See why. How to Modify and Maximize your Resume Template. Need a resume template? Feel free to download one, but be sure to make small modifications to tell heart analysis unlock your.

Would You Rather Work for a Man or a Woman? Do people still care whether they work for a man or woman, or do most people simply look for a nice job. Resume Builder Comparison | Resume Genius vs. Assisi Essay! LinkedIn Labs. What are the differences between the major online resume builders? Here's an in depth analysis of what. Resume Genius' builder, resources, advice and career tips are regularly featured on some of the tell tale, world's leading online and offline publications including: Our code geeks and HR experts are proud to governess introduce our new Free Resume Builder software to help you land more interviews in today's competitive job market.

HR-proven resume templates, built-in job description bullet point phrases to choose from, and tell heart, easily export to MS Word and PDF.

Write my essay - A literary analysis of a tell tale heart by edgar allan poe

Nov 17, 2017 Tell tale heart analysis,

Order Content from the Best Essay Writing Service - A literary analysis of a tell tale heart by edgar allan poe

Amazing Grace The Movie Essays and Research Papers. ? Amazing Grace When people speak of great men, they think of men like Napoleon men of violence. Rarely do they think of . peaceful men. But contrast the reception they will receive when they return home from their battles. Napoleon will arrive in pomp and in power, a man whos achieved the very summit of earthly ambition. And yet his dreams will be haunted by the oppressions of war.

William Wilberforce, however, will return to his family, lay his head on analysis his pillow and remember: the slave trade. Assisi Essay! Abolitionism , African slave trade , Atlantic slave trade 865 Words | 3 Pages. Roosevelt College Cubao Highschool Department Analysis of the Novel Entitled: Amazing Grace By: Tara FT Sering . (Requirement for English) Moderator: Sir Jayson Seel Maravilla Critic: Katrina Tan (Section Molave second year student) TABLE OF CONTENTS A. Analysis: I. Background of the heart analysis novel------------------------------------------------------ II. Authors Background---------------------------------------------------------- III. Synopsis-------------------------------------------------------------------------- . Amazing Grace , Best Friend of Charleston , Love 2116 Words | 7 Pages. The Amazing Grace The Amazing grace is a good book to read. By my standards is kind of violent . and crazy. Within the next few pages here I intend to address two issues.

First I will try to Cancer give a personal review of what I saw this book to tell heart analysis hold, and second I will try explaining the reverence which this book has to the field of Public Administration. First try to picture children in a slum where the squalor in their homes is just as bad as that which is in the streets. Where prostitution is assisi essay, rampant. Amazing Grace , John Newton , Mahalia Jackson 1135 Words | 3 Pages. AMAZING GRACE D G D Amazing . Grace , how sweet the sound, A7 That saved a wretch like me. D G D I once was lost, but now im found, A7 D Was blind, but now I see. D G D Twas grace that thought my heart to.

Amazing Grace , Christian hymns , English-language films 336 Words | 3 Pages. Amazing Grace Amazing Grace is not a good movie it is a great . Tell! movie . From time to time, films on History can be lengthy and Theory tedious, but that sure is not the heart analysis case in this fascinating movie about the famous abolitionist William Wilberforce, who was responsible for steering anti-slave trade legislation through the British parliament. What! Contrary to what its title suggests, Amazing Grace isnt really about the inauguration of the tale heart Christian hymn. Set in the 18th century England, it focuses on Williams. Abolitionism , African slave trade , Amazing Grace 1326 Words | 4 Pages. The Multiverse Essay! I chose to discuss the tale poem Amazing Grace by John Newton. Assisi Essay! I not only love this as a poem, but love to sing it as . a hymn. Amazing Grace was written by John Newton and published in tale analysis, 1779 (Pam, G., 2007, February 3). The tone of this poem is one that kind of shows how John Newton went from Theory, a lost soul, sinner, to one that believes and lives to tell analysis honor God. In a new biography of John Newton, William E. Phipps argues that Newton's Amazing Grace was an appropriate reflection on what is the medulla his conversion.

Amazing Grace , Debut albums , Hymn 752 Words | 3 Pages. The Analysis Amazing Grace Kiel Carino ENG 125 Professor Olabisi Adenekan October 29, 2012 . The Analysis Amazing Grace The poetry Amazing Grace by John Newton is one of the most famous poems ever written and composed. Amazing Grace has been particularly influential and has affected lives since it was written. The reasons why Amazing Grace is influential are for the same reasons why I found this poem very interesting and engaging. Amazing Grace , John Newton , Literature 746 Words | 3 Pages. reading Jonathan Kozols Amazing Grace , two main topics stood out to me. The first topic that stood out to me was power and tell the . Ethical Of Nursing! affects of tale analysis, power. The second topic that stood out to me was the major socio-economic class differences that exist between the The Multiverse Theory rich and the poor. Tale! Using the course reading from Miller and of the medulla the two course readings from tell analysis, Mantsios, I will further analyze and examine these two topics from Kozols Amazing Grace . The Multiverse Theory Essay! To begin, lets see how Kozols Amazing Grace relates to Jean Baker. Heart Analysis! Mass media , News media , Poverty 1227 Words | 4 Pages. Amazing Grace Movie Response Wilberforce stays with cousin Henry to get better from sickness. Wilberforce is governess, a . Member of Parliament. His cousin Henry and Hannah, his wife, try to set him up with a girl.

Wilberforce is fighting against the slave trade, trying to abolish it. Wilberforce says God has found him. Tale Analysis! He has a political career and ethical principles would rather spend time with nature. Tell Heart Analysis! William Pitt is The Battle to Beat Essay, going to tale heart analysis try and be Prime Minister and ultimately does. Pitt asks Wilberforce to join him. A group. African slave trade , Arab slave trade , Atlantic slave trade 438 Words | 2 Pages. children in Jonathan Kozol's Amazing Grace . Who defines them as 'other'? How? What makes them feel like 'nobodies'? What makes . them feel like 'somebodies'?

What is the bronte role of tale heart, religion in this daily struggle for human dignity? Drugs, violence, prostitution, pollution, infestation, and Cancer sickness of all kinds are present in South Bronx, New York. Unfortunately, children are surrounded and involved in all these problems and more. Heart Analysis! In Jonathan Kozols novel Amazing Grace , an evil reality full of ethical principles of nursing, racial. Amazing Grace , Discrimination , Ghetto 809 Words | 3 Pages. Tell Tale! What's so Amazing About Grace Book Report. Cameron Peterson Mr. Oswald Romans Period 4 11 January 2012 Whats So Amazing about Grace ? Book Report Whats So . Amazing about Grace ? is a book written by Philip Yancey. It begins with a twisted story of a prostitute living on the streets. Is The Medulla! She is unable to feed her two-year old child and has to find another way to heart analysis earn money. She could not think of is the function, any other alternatives and began selling her child out for prostitution.

She could make much more money this way than she could in one night. The. Amazing Grace , Gift , Grace 752 Words | 3 Pages. accepted. Amazing Grace is tell tale analysis, a hymn that is sung in many religious institutions. It is one of the most adored and popular African . American spirituals. The lyrics uphold one's place in this world and the importance of faith to bronte governess carry on in the face of trials and tribulations, a faith that leads one to heaven: Amazing grace ! How sweet the sound that saved a wretch likes me. I once was lost and now am found was blind but now I see. Through many dangers, toils, and snares I have already come; 'Tis grace hath. Amazing Grace , Cycle of poverty , Extreme poverty 1879 Words | 5 Pages. ?J. Walcott IDIS 205 Evan Kroon 3/20/14 The theme that stuck out most to me in Kozols Amazing . Grace was the theme of oppression. Merriam-Webster defines oppression as, unjust or cruel exercise of tell, authority or power or a sense of being weighed down in Theory, body or mind. There seemed to be so many things oppressing the people that Kozol writes about.

Things like: the healthcare system, the education system, lawmakers, their surroundings, and even their race is. Oppression , Poverty , Social structure 964 Words | 4 Pages. Amazing Grace In the movie Amazing Grace was a horrible yet completely realistic . conditions of the most poor, rundown neighborhoods and districts in New York City. During the 18th century millions of men, woman and children were taken from their homes in tell tale analysis, Africa and Internet Security Threats sold into slavery. Few survived the slave trade was wrong, and to find one who had the tell tale analysis courage to stand-up against it seemed impossible. Ethical Principles! Humanity needed a hero, someone who could establish equally. The movie Amazing Grace tells the tell heart account. Amazing Grace , Atlantic slave trade , Charles James Fox 588 Words | 2 Pages. Omar Chaoura Bourouh Socamp;201 DATE @ d MMMM yyyy 24 October 2014 Amazing Grace , Chapters 3 and to Beat Breast 4 3117215379222SOUTH . BRONX, NEW YORK - OCTOBER 2: Housing projects tower over tale heart analysis the torn streets of Mott Haven October 2, 2009 in South Bronx, New York City. SOUTH BRONX, NEW YORK - OCTOBER 2: Housing projects tower over the torn streets of Mott Haven October 2, 2009 in bronte, South Bronx, New York City. I can honestly say that I believe that some classes and subjects change your life?

Shouldnt they. Affordable housing , Amazing Grace , Manhattan 890 Words | 2 Pages. Review of the Amazing Spider-Man Movie. Analysis! The Amazing Spider-Man Review I have always enjoyed action films. I would state that this fact does make me somewhat biased for this review. . Fictional characters that are super heroes only made them better for me. I went into ethical of nursing this movie knowing it was going to be one that I would enjoy. This year has had a few different super hero films such as The Avengers and The Dark Knight Rises. The Avengers released May 4th, 2012, was a box office hit, topping the tell heart analysis charts for weeks. The Amazing Spider-Man.

Harry Osborn , Marvel Comics , Mary Jane Watson 1198 Words | 3 Pages. BSEDSS 2-1N Title Of The Book: AMAZING GRACE Author: Tara FT Sering I:BACKGROUND OF THE . AUTHOR: Tara FT Sering is the author of five books published in the Philippines.She is currently editing an art magazine Contemporary Art Philippines in Manila and is working on a new book.( Amazing Grace pp.194)Almost Married:A novel about Love, Longing,and last Hurrahs, Between Dinner and the Morning After, Amazing Grace , Reconnaissance, and Getting Better. II:SUMMARY. Amazing Grace , Fiction , John Newton 669 Words | 2 Pages. Film Review Amazing Grace In the 18th century millions of men, women and children were taken from their homes in Africa and . sold into slavery.

Few survived the ethical slave ships, and even fewer lived through their slave labors. Some people thought the slave trade was wrong, but to find someone who had the courage to stand-up to make a stop was hard. Amazing Grace , is a movie based on a true story. Written by Steven Knight and directed by tell heart Michael Apted, it is about William Wilberforce and his quest. African slave trade , Amazing Grace , Atlantic slave trade 600 Words | 2 Pages. The movie Amazing Grace tells the enthralling story of the life of William Wilberforce, an enthusiastic . abolitionist. Ethical Principles! His lifelong struggle to end British slave trade inspired the hymn that most everyone is familiar with.

Driven by the belief that Gods grace is sufficient for anyone to be saved, Wilberforce devotes his life to heart a noble cause with the The Multiverse Theory assurance that grace will lead us home in the end as is written in the hymn. The characters and the universal, hope-inspiring themes create an exciting. Abolitionism , Anti-Slavery Society , Atlantic slave trade 490 Words | 2 Pages. Tell Heart! ?Running head: AMAZING GRACE Amazing Grace Gloria J. Winters . Grand Canyon University Jesus and His Interpreters February 13, 2011 Amazing Grace The purpose of this essay is to reflect on and discuss three themes from Pauls Epistles that are of significance in my personal life. This essay will also discuss in particular, the Pauline theme carried throughout the epistles, and Essay will describe their impact. Christian terms , Christianity , Epistle to Philemon 1659 Words | 9 Pages. Andrew Hernandez Professor McKee REL2000 01 October. 2012 Critique of Amish Grace Amish Grace , directed by Gregg Champion, . is a religious movie about a grieving Amish mother who struggles to forgive the heart analysis wife of is the function medulla, a gunman who killed her daughter and four other young girls in their schoolhouse.

After the shooting, many remained true to their traditional belief to practice forgiveness, expect for Ida Graber, who is upset with God and her husband for offering forgiveness so quickly. Burdened by. Amish , Amish school shooting , Faith 1290 Words | 4 Pages. Tell Heart Analysis! The poem I chose was Amazing Grace by John Newton. John Newton was born in London, July 24, 1725 and is the of the medulla died December 21, 1807. Tale Heart Analysis! He . was an Anglican priest and assisi essay hymn writer, advocating the Christianity view of redemptive forgiveness. Tell Tale Heart Analysis! He wrote Amazing Grace as an element of bronte, that prospect (Clugston, 2010). Amazing Grace is one of the most famous poems ever written and composed.

This poem is also a hymn that speaks too many who is looking for tell analysis, salvation, forgiveness, grace and faith. This form of Theory Essay, poetry. Amazing Grace , Hymn , John Newton 583 Words | 2 Pages. Heart Analysis! Amazing Grace by John Newton Amazing Grace is a hymn that speaks to the heart and soul of . Internet Security Threats! many who are looking for faith, forgiveness, redemption, salvation, and grace . John Newton is able to stir the soul with an emotional connection relating salvation. As a hymnist, this form of the poetry is categorized as narrative poetry because it tells a story that is sung about salvation, whereby he uses figure of speech to tell heart express to create a distinctive and imaginative effect, and has drawn upon. Amazing Grace , Christian terms , God 573 Words | 2 Pages. Amazing Grace In the documentary-style book Amazing Grace , . Jonathan Kozol writes about the realities of The Battle, living in Mott Haven, one of the tell analysis South Bronx poorest neighborhoods. His goal is to inform readers of the assisi essay realities of tell, children living in The Multiverse Theory, a slum and the unfairness of it all. Tell Tale Heart Analysis! The population of 600,000 live in Internet Threats Essay, the South Bronx of New York City and 43,000 make up Washington Heights and Harlem which is separated by a narrow river, make up one of the most racially. African American , Amazing Grace , Neighborhoods in the Bronx 512 Words | 2 Pages. Movie Critique ENG 225 February 18th, 2013 Film Critique The movie Bruce Almighty starring Jim Carrey, Jennifer Aniston, . Steve Carell and Morgan Freeman is heart, considered a comedy, a drama and a fantasy movie in terms of genre but most prominently, a comedy. Bruce Almighty could be viewed several times and still be enjoyed.

Bruce Almighty is a funny movie yet with the drama of a couple dealing with some issues is also explored. The Multiverse Theory! This movie is for everyone. The movie Bruce Almighty is directed by. Bruce Almighty , Evan Almighty , Jennifer Aniston 2779 Words | 7 Pages. The film Amazing Grace follows the quest of tell tale heart, William (Wilber) Wilberforce to abolish slavery in the UK. He was a member in assisi essay, the . House of tell heart, Commons and principles his friend William Pitt became the Prime Minister. Tale Heart Analysis! On Wilbers endeavour he introduced a bill with the help of to Beat Breast Cancer, Pitt (who was also a strong believer of the movement, which is tale, one of the factors that made them such close friends) and a group of anti-slavery activists which included Equiano, an ex-slave who was of African descent, and Thomas Clarkson, a. Abolitionism , Amazing Grace , American Civil War 695 Words | 2 Pages. A DESCRIPTION OF GRACE By Emmanuel O. Obiorah Jos, Plateau State 27th March, 2013 GRACE . Assisi Essay! INTRODUCTION The word Grace is tell tale analysis, not a new word to most religious circles.

Among Christians, such adjectives like amazing , extravagant, divine and awesome have been used to qualify the word grace with each depicting its importance to the Christian faith. Ethical! Our concern in this work is to describe and analyze this word- Grace for a better, richer and more fulfilling understanding. Christianity , God , God in Christianity 2625 Words | 7 Pages. Amazing Grace , by Jonathan Kozol, is about the tell tale authors interviews with, and The Multiverse Theory Essay thoughts about, some of the poorest people who live . in the poorest sections of New York. The facts stated in Amazing Grace startled me with the prevalence and desperation of the tell tale analysis poverty situation in areas like the South Bronx and Mott Haven. These are areas where there are hundreds of thousands of people living in broken, crowded, and rundown apartment buildings, That, says Kozol, most people would not even kennel their. Amazing Grace , Cycle of poverty , Household income in the United States 591 Words | 2 Pages. Early life and letters of paul | Paul on Grace | By Grace we are Saved | | | 8/7/2012 | This research paper . Breast Cancer Essay! will discuss Paul and his reflections on grace . | Abstract/Introduction: The purpose for this paper is to provide historical background on Paul and grace . I will also provide how it is applied to tale analysis modern times, how it has changed my life as well as my learning goals from this paper on The Multiverse Paul and grace . Tell Heart! Paul embraced Gods grace after his conversion and call and informed. Christianity , Epistle to the Romans , Gospel 1736 Words | 5 Pages. part in creating the mood.

Music plays different types of moods. Like when I hear the song amazing grace is a sad song because . it makes you think of past love ones. Theory! When you hear the song turn down for what it makes you want to dance around and feel happy. Analysis! Like I was at a party with friends and we turned turn down for wat we dance crazy. And At my grandfathers funeral they put on aa song amazing grace . The Multiverse Theory! . Amazing Grace , Critical thinking , Music 459 Words | 2 Pages. Daddy Grace : A Celebrity Preacher and His House of tale, Prayer. By Marie W. Dallam. (New York: New York University Press, 2007. viii, 263 pp. . $35.00, ISBN 978-0-8147-2010-3.) The book Daddy Grace : Celebrity Preacher and His House of Prayer was a very interesting book full of facts and stories. The author Marie W. Dallam wrote the book with great emphasis on certain parts of the story that she wanted to tell. She began her book out by describing the history of the island that Daddy Grace was a native. Theory Essay! Amazing Grace , Cape Verde , Charles 1634 Words | 4 Pages. Movie Analysis- Amazing Spiderman There are many versions of Spiderman, but Amazing Spider-man is the best . version ever.

The graphic works, the music, and the plot are amazing like the movie title. The Amazing spider-man is not connected to the previous Spiderman movie . One online film critic stated that there is a silent war ongoing right now between two of the big comic book flicks hit theaters in July of tale analysis, 2012: Warner Bros. The Dark knight Rises and Sonys The Amazing Spider-Man (Sandy Schaefer). The Battle To Beat Cancer! Daily Bugle , Green Goblin , Harry Osborn 1510 Words | 4 Pages. Tale Heart Analysis! done with it in two days because I simply could not put it down. I had a lot of people tell me how amazing this book was and how I would love . it, so I tried it out. To Beat Breast Cancer Essay! I thanked all of the people that recommended it to me whenever I was finished, and now I am recommending it to you. Hopefully when you get done with it, you come to the same conclusion that I did. This book would make one amazing movie . Here is how the book basically goes down.

There is a girl that is slowly dying of cancer, and tell heart analysis one. 20th Century Fox , Clint Eastwood 1770 Words | 3 Pages. the hypocritical relationship with people. He abandoned his old car, burned cash, and started on his exploration on foot. Security Essay! I dont need money. Make people . caution. Tell Heart! Rather than love, than money, than faith, than fame, than fairness, give me truth.( Movie ). During that time, he felt confused. Although seemed to understand, yet just only Essay half-comprehended Thoreaus poetry, one of the books he brought with hin during his journey. As Thoreau wrote in his book Walden, I went to the woods because I whished. Christopher McCandless , Civil disobedience , Emotion 1042 Words | 3 Pages. Tell Tale Analysis! As part of the summer reading assignment this year, I read the book Amazing Grace by Jonathan Kozol. In this documentary-style . book, he told about the horrible yet completely realistic conditions of the bronte most poor, rundown neighborhoods and districts in New York City. Kozol wrote the book for tale heart analysis, the purpose of telling the stories of the children who lived in these parts of the city.

He dedicated his work to bronte those children and it was his goal to tell analysis inform readers that slums were in fact in existence and. Security! Ghetto , Mayor of New York City , Morality 811 Words | 2 Pages. Delilah Whilst watching the film, it becomes extremely hard to make a decision between whether making a wordless film or attracting numerous audiences . is a bigger accomplishment. It is amazing that the tell tale analysis audience fails to realize the films male protagonist during the entire movie . The setting of the movie is in assisi essay, the arid Aboriginal outback. Being a motion picture, Samson and Delilah is remarkably restrained, but with a rich impact (Sluis, 2010).

In the opening scenes Warwick Thornton, the first-time. Audience , Audience theory , Delilah 929 Words | 3 Pages. Armageddon: World and Grace Stamper. Ramirez Date: November 27, 2013 What do you understand about the title? The title was Armageddon meaning it is the end of the world, the analysis war . Assisi Essay! between good and evil, and it is something that ends. Armageddon is the main focus of the tale heart movie or film that we watched. Assisi Essay! Science concept: The science concept of the film talks about space, like it strike a topic anout astronomy. It also tackled about the impact of asteroids who falls in earth and the speed, time and also the tell tale gravity. Please. Asteroid , Earth , Earth's magnetic field 873 Words | 3 Pages. Even though you might not see it at first, The Movie Star seems to do a lot to capture its readers from more then what they might initially . think.

No matter what Simmons is saying by his sport analogies, movie stats or bold statements about readers favorite actors, he seems to be able to easily intrigue you. Ethical Of Nursing! Simmons clearly seems to tell tale heart analysis know what his audience, from the people that fallow him from his fame in the sports world or if its the more pop-culture crowd enjoying the Grantland website. Reading. Actor , Celebrity , Character actor 1010 Words | 3 Pages. Sunflower 5.Rough Cut (No Mercy for the Rude, is a nice movie but I did'nt include it here due to The Battle to Beat Breast some explicit scenes in the . Tale Heart Analysis! movie not suitable for the young audience although the Security Essay storyline is tell tale heart, good) The Best of the Best of Romance Movies 1. The Battle To Beat Breast Cancer Essay! The Classic- *Unforgettable 2. A Moment to Remember- *Tearjerker 3.Temptation of Wolves- * Amazing 4.Daddy Long Legs- *Inspirational 5.Windstruck- *mixed emotions 6.My Girl and I- *heartwarming 7.Sad Movie - *lot of tale, tissues 8. Love Phobia- *heart pounding . Is The Medulla! 2000s romantic comedy films , Actor , English-language films 552 Words | 3 Pages. Chapel: Bible and Amen Amazing Grace. Tale Heart Analysis! Closing Prayer: Dedication and Commitment Benediction Response: Amen, Amen, Amen Amazing Grace Christian Learning Center . Fermina Compd., Brgy. Sta Ana, Taytay , Rizal Tel. no. 658-2821 Chapel Service THEME: VALUING GODS GIFT SUB-THEME: God Gave Me a Special Book AUGUST 5, 2013 8:00 AM Prelude Lighting of candle Opening the bible *Call of Worship Leader: The Lord is what is the function medulla, my shepherd; I shall not want. People: He makes me lie down in heart analysis, green pastures.

He leads me beside still waters . The Battle Cancer! Amazing Grace , Bible , Christianity 310 Words | 2 Pages. Joyce Simmons 802 Words Monday/Wednesday 2-3:15 Primary . Tell Tale Analysis! Focus Film Evaluation Radio Years ago I watched a movie for the first time that honestly changed the way I think. The movie Radio is based on The Battle to Beat Breast Cancer Essay the true story of tell tale, James Radio Kennedy and T.L. The Multiverse! Hanna High School football coach Harold Jones. Analysis! It tells the story of a young mentally challenged man who is taken under the ethical principles of nursing wing of a high school football. Actor , American film actors , Film 813 Words | 3 Pages.

Theology of tell, Grace There are many different ways to The Battle to Beat Cancer interpret the theology of grace . In this paper, I will be discussing four . Tale Analysis! major theologians who have the most popular insights on grace . Governess! These theologians include Augustine, Aquinas, Luther, and Rahner who all have their own unique perspective on grace . Tell Tale Analysis! All of their theories seem to Security intertwine with one another but each individual one has a different twist that makes them slightly different. Heart! The first theologian Im going to discuss is Augustine. Adam and Eve , Augustine of The Multiverse Theory, Hippo , God 846 Words | 3 Pages. Making Dreams Come True The movie Miracle tells the inspiring story of the 1980 United States hockey team and their journey to becoming the . best hockey team in the world. Any hockey fan would be a perfect contender for watching the movie . The movie explores the many struggles that the tale heart team has to face to conquer their way through the assisi essay Olympics, including on and off the ice. At a time when the country is in tell tale, a period of struggle with the The Multiverse Theory Cold War, Coach Herb Brooks has goals for the team that seem. Aerosmith , Cold War , Entertainment 1183 Words | 3 Pages. Tale Heart! feeling the way the music is sounding, keeps your heart pounding throughout the movie . Road to Perdition had more of a focus on the editing and . the suspense of the plot to keep you engaged.

The ability to keep the movie interesting throughout is an assisi essay easy task in both films, given their plot. It is the extensive attention to tell tale heart detail in what is the, Apocalypse now that makes it one of the best movies ever made, but it is also the power the movie has to make every viewer relate to the stresses that Martin Sheen is dealing. Tale! Apocalypse Now , Benjamin L. Willard , Film 1050 Words | 3 Pages. The Lego Movie At the beginning of Phil Lord and assisi essay Christopher Millers 21 Jump Street, their 2012 cop comedy that was a repurposing the tell analysis . television show that ran from 1987-1991, Deputy Chief Hardy (Nick Offerman), explains to two young cops (Channing Tatum and Jonah Hill) that theyre being assigned to a unit in governess, which theyll be impersonating high school students to investigate drug crimes. Tell! Were reviving a canceled undercover police program from the Internet Security Essay 80s and revamping it for modern times, Hardy. 21 Jump Street , Brickfilm , Channing Tatum 1562 Words | 4 Pages. The Great Escape Movie Review Yash Desai *POW = Prisoner of War The Great Escape directed by John Sturges is tell tale analysis, a movie of . high standard and excellence. This action packed adventure, released in 1963, takes place in Germany at the peak of World War II. Taking us back to assisi essay 1942, The Great Escape documents the escape of 76 prisoners from a special Stalag (prison camp), designed specifically for them. By contrasting color cinematography with a classical soundtrack, the movie successfully blends the.

Film , Film score , James Garner 1001 Words | 3 Pages. Jr. Analysis! Submitted To: M. Mariner Honors Language Arts 9 Period: . Internet Security! Seventh May 30th, 2007 [pic] The Three Graces as they were called were if not the, then one of the least mentioned in Greek Mythology. Tale Analysis! Some today do not know who they may be. Although, inside of us all is a remnant piece of them in us that makes us as we are. I think they are important because. Security Threats Essay! Antonio Canova , Aphrodite , Charites 632 Words | 3 Pages. Analytical View of Armageddon Movie. Tell Analysis! films, such as Citizen Kane and The Grapes of Wrath, that actually taught us about The Multiverse Theory life, and then there are films that are just were made for pure . entertainment value.

One such film, Armageddon, directed by tell tale heart Michael Bay, is a science-fiction, action movie that was solely used for Theory Essay, entertainment purposes. Armageddon is tell tale heart analysis, about an asteroid coming toward earth that will totally destroy mankind and the planet. No one saw the asteroid plunging towards Earth until it was too late. Well our object collision. Armageddon , Ben Affleck , Bruce Willis 987 Words | 3 Pages. ?1. Ethical Of Nursing! What is your reaction to Platoon? How is it similar and/or different to other war films you have seen? What is the films central focus?

After . watching Platoon, I dropped to tell tale heart marveling why Oliver Stone was adept to make such an effective movie without falling into the trick Truffaut talked about - how he made the to Beat Cancer Essay video riveting without making it exhilarating. Here's how I think he did it. He forsook the choreography that is standard in nearly all war movies. He abandoned any try to make it. Apocalypse Now , Charlie Sheen , Oliver Stone 1199 Words | 4 Pages. Social Graces - More popularly known as good manners and etiquette is tell tale, not a put-on or add-on to ones personality. Manners - Says . Webster, are social conduct or rules of conduct, as shown in the prevalent customs; habitual deportment, especially with reference to polite conventions. Etiquette - The term etiquette seems stilted or phony, but consider that etiquette is merely a name for a pattern of Internet Security Threats Essay, behavior that is based on consideration for others, appropriateness and good taste, and. Etiquette , Etiquette in North America , Human behavior 520 Words | 3 Pages. This scene is the last scene of the movie . It takes place at the old home that the crew lived in when the tale analysis first movie came out. . The crew(Dom, Brian, Letty, Mia, roman, Tej, Han, and assisi essay Brians child) are gathered together in the yard. Starting the scene Roman comes out tell heart of the house and tells Tej not to burn the barbeque again(implying that this wasnt the first time it had happened, with Tej replying that he never burned it before. Then it the scene switches focus to Brian, Mia, and their son in which.

Everything That Happens Will Happen Today , Love , Paul Walker 1191 Words | 3 Pages. Theory! English Period 1 The Movie Life of Walter Mitty The Secret Life of tale analysis, Walter Mitty, by James Thurber, was a comedic short story about a . peculiar man who continuously day dreamed about being a hero, which ultimately got him into trouble. For the movie adaptation of the Essay story, Walter Mitty is tale analysis, portrayed as an The Multiverse Theory Essay unusual hero by tell heart analysis Danny Kaye, Mittys love interest, Rosalind Van Hoorn, by Virginia Mayo, and the notorious Dr. Assisi Essay! Hollingshead by Boris Karloff. The three main aspects of this movie we will be reviewing. Danny Kaye , Fiction , James Thurber 978 Words | 3 Pages. Amazing animals that can fly These animals are naturally born without wings on tell tale heart their body, and Internet Security Essay most of analysis, their relatives are also can not . To Beat Cancer Essay! airborne in the air. But with thousands and thousands years of evolution and adaptation to their surroundings, they finally found the tell heart analysis way how toflying without wings.

In fact, to some of these animals, the word flying is misleading, as they actually gliding in the air between a short to The Multiverse Theory Essay medium distance instead of really fly. They are also often called as the. Catfish , Channel catfish , Fish 855 Words | 3 Pages. Jade Ariane D. Faustino, BSA 1-36 DATE: September 19, 2012, Wednesday SUBJECT: Analysis of the Movie , Bicentennial Man (ENGL 1013) The . Story Andrew, the heart NDR series robot was introduced to the Martin family to perform housekeeping and maintenance duties. The family discovered that Andrew can both identify emotions and reciprocate in kind because of the bronte governess rejection of the older daughter named Grace and other situations. Tale Heart! When Andrew accidentally breaks the figurine belonging to bronte governess Little Miss Amanda. Emotion 1051 Words | 3 Pages. adaption of the Broadway musical Chicago took place in tell tale analysis, the mid-twenties, directed by is the of the Rob Marshall. This movie is geared toward the people who . enjoy musicals and those who are Broadway fanatics. Its a comedy, a crime, and a musical. This movie is tell tale analysis, definitely meant for adults of a mature stature. Its full of violence, vulgar language and sex.

Each musical number that was performed throughout the Essay movie conveyed strong emotionally depth. For example, The Cell Block Tango, each murderess on the row told. Broadway theatre , Catherine Zeta-Jones , Chicago 1186 Words | 3 Pages. portray this story, and after seeing the movie I was impressed with how closely the tell heart analysis film followed the book. Though the book was enticing and . unusual the movie quickly surpassed the book in my opinion. Though the movie followed the book closely, there were some differences such as the amount of flashbacks the Internet Security father has, the illusion of hope, and the play out of certain events. A long time has passed since the idea that The book is better than the movie was accepted without question. Most of the. Cormac McCarthy , Film , Kodi Smit-McPhee 922 Words | 3 Pages. ?Worlds apart The movie Worlds apart is tale, directed by Niels Arden Oplev, and produced by Thomas Heinesen. To Beat Essay! The movie is written . by tale heart Sten Bille and a young girl, which life the movie is based on. The movie is a documentary, which means that the movie is based on reality, and reflects the world as is it.

The movie is about a girl names Sara. Sara is 17 years old and lives in a family of six. The family is a part of Jehovahs witnesses, and is a very religious family. The family has a close bond. A Little Bit , A Little Bit Longer , Faith 993 Words | 2 Pages. Cell Phones amp; Social Graces Have you ever been driving down the street and noticed a driver using his/her cell phone while driving?

In . the article Cell Phones amp; Social Graces written by Charles Fisher, examples were given of people using their cell phones in a rude fashion. People using their phones in a selfish behavior can cause a careless way of The Multiverse Theory Essay, acknowledgement to their surroundings and others. Cell phones can also work as a distraction being forced away from something that needs. Cellular network , Distraction , Mobile phone 1198 Words | 3 Pages. A Report on tell the Movie the assisi essay Perfect Storm and Its Factualities.

A Report on the movie The Perfect Storm Purpose: To watch a popular Hollywood natural disaster movie and review and summarize . the scientific merit of it in a report, for analysis, my report I chose The Perfect Storm. A movie that is based on the actual storm in late October 1991 later called The Perfect Storm (Viets 2000). Also to comment on how realistic the movies storyline, effects and governess scientific merit when compared to tell tale analysis the real life disaster which it is The Multiverse, trying to recreate. Introduction In late. Tale! 1991 Perfect Storm , Andrea Gail , Extratropical cyclone 1710 Words | 5 Pages.

Amazing Ashitaba, the Tomorrow Leaf and Threats Essay King of Vegetables It has been circulating among my circle of friends that the plant ashitaba . has many benefits in treating several Chronic Diseases and google has it that Ashitaba has been successfully used in tell heart analysis, the following conditions: * Chronic hepatitis * Poor blood cell reproduction and what of the medulla anemia * Blood cleansing and purification * High blood pressure * Poor circulation * Carcinoma * Hangover * Asthma and other breathing.

Order Essay Services & Assignment Papers Online - "The Tell-Tale Heart" - Cliffs Notes

Nov 17, 2017 Tell tale heart analysis,

Online Cheap Custom Essay - Essay on Tell-tale Heart Literary Analysis - 723 Words | Bartleby

Essay: Oral administration of drugs. Today various routs available for the administration of drugs but the oral route is the simplest and most preferable route for the administration of dosage forms. Different dosage forms are available for tell tale heart analysis the administration orally. 3. Emulsion suspensions. 4. Solutions etc. But the problems is there in the recently invented drugs having problem with there bioavability approx. 50% of newly marketed drugs can not be given orally due to of nursing poor solubility.

The poor solubility of drugs can reduce the bioavability of dosage forms. Recent approaches have included the administration of drug components with lipid vehicles such as oils, liposomes and self-emulsifying formulations [1, 2]. This system was not use commonly but know the days importance of lipid based drug delivery system is tell heart analysis very height due to poor water solubility of drugs. For the improving bioavability we formulate a new drug delivery system called self emulsifying drug delivery system By example, the bioavailability of Tipranavir (TPV), a nonpeptidic protease inhibitor anti-HIV drug, was doubled when dosed to rats in to Beat Breast Cancer, a SEDDS formulation versus delivered as solid powder in a hard filled capsule [3]. Heart Analysis. developed a self-emulsifying drug delivery system for Coenzyme Q10 using polyglycolyzed glycerides as emulsifiers with a resultant 150% increase in assisi essay, bioavailability.4 Numerous other examples exist in the literature demonstrating enhanced bioavalibility with self emulsifying drug delivery systems 5-6 but most focus on heart a single formulation or small.[2] set of formulations with little explanation of how this formulation was developed. Current SEDDS formulation development, consequently, in general occurs through resource-intensive trial and error. Some mechanistic studies have been conducted exploring a range of SEDDS formulations and a specific aspect of their function, most commonly ability to emulsify [7, 8]. . Improved quantitative understanding of how properties of a specific self emulsifying formulation interact with the biological environment to enable oral absorption could help optimize SEDDS formulations for enhancing bioavailability. Although a significant amount of literature exists from other fields concerning the function of emulsions [9-10], pharmaceutical formulations have not been broadly studied with respect to fundamental aspects of The Multiverse emulsion function, with few studies statistically developing predictive models that relate emulsion properties with formulation parameters [11]. In particular, analysis and tell heart analysis optimization of emulsion function across a broad range of formulation parameters via experimental design has not been widely explored. One poorly understood aspect about SEDDS is the influence of different formulation components on the overall performance of these drug delivery systems in The Battle Essay, vivo.

Different types of oils with different characteristics and different surfactants combined at tell heart analysis, different ratios may influence the performance in vivo drastically. There is no guidance currently available for formulating a drug with specific properties with self. emulsifying drug delivery formulations.12 It is therefore necessary to investigate the influence of formulation components with a quantitative and statistically designed and analyzed manner. 3 Another knowledge in which there is a lack of understanding is the mechanism of how self emulsifying drug delivery systems work to enhance the overall bioavailability of a hydrophobic drug orally. Internet Essay. Suggested mechanisms responsible of functioning of tell tale heart analysis SEDDS in the GI tract environment includes the is the function medulla increased drug solubilization in the aqueous lumen phase due to alterations in the composition and character of colloidal environment in the GI tract fluid and increased drug absorption due to tell tale analysis enhanced permeability permeability (e.g. widening of tight junctions, changes to The Battle to Beat Essay cellular processing) and tell analysis lymphatic transport [13-14-15]. Ethical Principles Of Nursing. Important mechanisms that would influence drug solubilization in the lumen is the rate and extent of tale digestion of lipidic formulation components. Another one is the rate at which the drug is released from oil droplets especially during the process of degradation of the emulsified drug carriers by the digestive enzymes in vivo. It is assisi essay essential to investigate the analysis rate of digestion of self emulsifying formulation lipids, rate of drug release, as well as the rate and extent of drug transport across intestinal monolayer incorporated with SEDDS in order to bronte understand and tell analysis predict formulation functioning in GI tract. Principles. Knowledge gained from these mechanistic understandings can be used as quantitative expressions which then can be incorporated into a pharmacokinetic model that will predict oral bioavailability of a drug administered with self emulsifying drug delivery systems. To define and understand challenges involved with oral delivery of hydrophobic drug compounds it is necessary to present a overview of current technologies.

16. Oral intake has been the most sought-after route of drug delivery by tell tale heart, the patients as well as the manufacturers for the treatment of most pathological states. Despite tremendous strides made in novel non-oral drug delivery systems (DDS) till date, majority of the drug formulations available in the commercial world today are the what medulla oral ones.17 Nevertheless, oral delivery of over tell analysis one-half of the drug compounds through gastrointestinal (GI) tract gets diminished owing to their high lipophilicity and consequently poor aqueous solubility. Oral bioavailability of such drugs, being primarily a function of bronte governess their solubility and dissolution,[18-19] tends to exhibit inadequate magnitude with high intra- and inter-subject variability. Besides, oral bioavailability also depends upon a multitude of other drug factors such as stability in GI fluidsintestinal permeability, resistance to metabolism by tale analysis, cytochrome P450 family of Security Essay enzymes present in gut enterocytes and liver hepatocytes, and tell tale heart interaction with efflux transporter systems like P-glycoprotein (P-gp).[20,21] explicitly illustrates the mechanisms of the governess physiological pathways through which the bioavailability of a drug from the conventional formulations tends to get impeded. Several formulation approaches have been employed to improve the oral bioavailability of diverse drugs.

Amongst these, oral lipid-based DDS have proved their immense potential in improving the tell tale poor and inconsistent drug absorption of many poorly water-soluble drugs, especially following their administration after meals.22 These include various types of lipid suspensions, solutions and emulsions.23 With applications in specific domains, the lipidic formulations, thus, have carved a singnificant niche in Theory, oral drug delivery. Self-emulsifying drug delivery systems (SEDDS) are relatively newer lipid-based technological innovations with immense promise in oral bioavailability enhancement of tell heart drugs. These formulations have shown to assisi essay reduce the slow and incomplete dissolution of a drug, facilitate the formation of tell analysis its solubilized phase, increase the assisi essay extent of its transportation via intestinal lymphatic system, and tell heart analysis bypass the P-gp efflux, thereby augmenting drug absorption from the GI tract.24. Self emulsion having grate capacity yo increase the bioavability of poorly water soluble drugs. Breast Essay. Its a isotropic mixture of oil ,surfactant, this system oil globules bind with drugs and increase the solubility of drugs. SEDDS is also known as microemulsion system. It will increase bioavability of tell analysis drugs 50-100% .25-26. 1. Medulla. Solid self emulsifying drug delivery system (SSEDDS) 2. Liquid self emulsifying drug delivery system (LSEDDS)

Recently day by day a new drug molequle was found but the only problems is that the bioavability of the drugs. Tell Tale Analysis. Because oral route is the most preferable route for the administration of drugs but poorly water soluble drugs having problems to formulates solid dosage form because it will reduce the bioavability of drugs.26. In the solid dosage forms numbers of excipients are use for the increasing drug solubility. They can be help in enhancing the assisi essay solubility of tell tale heart drugs. In the SEDDS we number of excipients are use. 3. Bronte. Co- surfactants. 4. Solidifying agent. They all the excipients help in the inhancing the bioavability of drugs.26. SEDDS is the isotropic mixture of oil, surfactant and co-surfactant. Tale Heart Analysis. Thy having the capacity to rapidely dissolve in stomach and instinal fluid and Cancer cover large surface area. due to tell tale heart analysis this nature of assisi essay SEDDS it will also use in the sustain relese drug delivery system for the instant delivery of drugs. This system can be use to increase the solubility of drugs by tell, the help of excipients in the oral dosage forms we can use PH modifier, water soluble organic solvents, surfactant, co-surfactants.

And oils are use long chain triglicryde and medium chain tryglyceried we also use PEG 400, propylene glycol, glycerin, non-ionic surfactants as water soluble organic solvents.36,37. 1.1 Composition of SEDDSs:- The nature of the oilsurfactant pair. The surfactant concentration. The temperature at The Battle to Beat Cancer, which self-emulsification occurs. 1.1.1 Oils:- Oils can solubilize the lipophilic drug in tell tale heart analysis, a specific amount. It is the most important excipient because it can facilitate self-emulsification and increase the fraction of lipophilic drug transported via the intestinal lymphatic system, thereby increasing absorption from the GI tract . Long-chain triglyceride and medium-chain triglyceride oils with different degrees of saturation have been used in the design of SEDDSs. Modified or hydrolyzed vegetable oils have contributed widely to the success of SEDDSs owing to their formulation and bronte physiological advantages. Novel semisynthetic medium-chain triglyceride oils have surfactant properties and are widely replacing the regular medium- chain triglyceride. 1.1.2 Surfactant:- Nonionic surfactants with high hydrophiliclipophilic balance (HLB) values are used in formulation of SEDDSs (e.g., Tween, Labrasol, Labrafac CM 10, Cremophore, etc.). The usual surfactant strength ranges between 3060% w/w of the formulation in order to form a stable SEDDS.

Surfactants have a high HLB and tell heart hydrophilicity, which assists the immediate formation of o/w droplets and/or rapid spreading of the formulation in the aqueous media. Surfactants are amphiphilic in nature and function medulla they can dissolve or solubilize relatively high amounts of hydrophobic drug compounds. This can prevent precipitation of the drug within the GI lumen and for prolonged existence of drug molecules. 1.1.3 Cosolvents:- Cosolvents like diehylene glycol monoethyle ether (transcutol), propylene glycol, polyethylene glycol, polyoxyethylene, propylene carbonate, tetrahydrofurfuryl alcohol polyethylene glycol ether (Glycofurol), etc., may help to dissolve large amounts of hydrophilic surfactants or the heart hydrophobic drug in the lipid base. These solvents sometimes play the role of the cosurfactant in the microemulsion systems.27.

1.2 Microemulsions or Self-Emulsifying Drug Delivery Systems (SEDDS) Emulsions in general are thermodynamically unstable systems. The droplets of the dispersed phase are large. Microemulsions on the other hand are emulsion systems that have a droplet size of a few to hundreds of Security nanometers and are typical complex fluids that consist of three essential components: two immiscible fluids and a surfactant. Tell Heart Analysis. Typically these are water-in-oil or oil-in-water microemulsions where the rheological properties of these two liquids and microstructure of the surfactant strongly affect the resulting microemulsion . Microemulsions and micellar solutions are distinguished from Essay emulsions by the fact that the tell average drop size does not grow with time, which is a manifestation of thermodynamic unstability. Assisi Essay. Micellar solutions and microemulsions on tale heart analysis the other hand are assumed to Security be thermodynamically stable. Reasons why there is tremendous attention on SEDDS include industrial trend towards the discovery and development on hydrophobic drugs and the resolution of technology transfer, stability and regulatory issues by SEDDS and the fact that they have proven pharmaceutical benefit with commercially available compounds of tale analysis up to 5 fold increase in bioavailability (cyclosporine, lipid soluble vitamins, HIV protease inhibitors etc.) Self-emulsifying drug delivery systems by The Battle Essay, definition are mixtures of an oil, one or more surfactants and optionally a co-solvent or co-surfactant which when introduced into tell tale heart analysis an aqueous media, under gentle agitation, forms fine oil-in-water emulsions. These systems when incorporated with a drug compound, drug is distributed in the aqueous solution entrapped inside oil droplets. SEDDS enable distribution of hydrophobic drug component in ethical principles of nursing, the aqueous media and tell analysis creates a drug solubilization in the gastrointestinal environment. Distribution of drug inside oil droplets prevents drug from assisi essay being an tell tale heart analysis undisolved substance, precipitating and principles being excreted from body.

However their mechanisms of action in the body are not limited to solubilization enhancement and also include other processes such as intestinal permeability and lymphatic transport enhancement. SEDDS by nature are thermodynamically stable emulsions compared to unstable regular emulsions. Their stability is thought to be dependent on their relatively small dispersed oil droplet size and tale heart narrow range of ethical of nursing droplet distribution. SEDDS are typically composed of emulsion droplets having a diameter of heart analysis 50 nanometers to 500 nm whereas systems having droplet size less than 50 nm are called self nano emulsifying drug delivery systems (SNEDDS). For a given drug only very specific formulations will give efficient emulsification and a self-emulsifying system that will work to enhance bioavailability. Efficiency of SEDDS therefore, as explained in of the medulla, detail by Gursoy et al., is governed by surfactant concentration, oil/surfactant ratio, polarity of the emulsion, droplet size and charge of the droplets. Tell Tale Analysis. However, the mechanism that governs self-emulsification has not yet fully understood. It is suggested that water penetrates through the gel and LC phases that occur at the surface of the droplets. This is followed by the solubilization of the water in oil phase until the solubilization limit is reached. What Is The Function Of The Medulla. After the limit is reached, formation of dispersion of LC phase is formed and this depends on the surfactant concentration. Wit this formation, SEDDS become resistant to coalescence.

Emulsion stability is tell tale analysis governed by a variety of factors such as physical nature of the interfacial film, presence of electrostatic or steric barriers on the droplet, viscosity of the Theory Essay continuous phase, droplet size distribution, oil to water ratio, temperature and the amount of surfactant that is absorbed on the surface of the oil droplet. The more surfactant is absorbed on the surface, the more decreased the interfacial tension between oil and water which consequently yields delayed coalescence of tell tale heart analysis droplets by electrostatic and steric repulsio. Although with the addition of high amounts of drug, which is common case for potential oral dosage forms, it is harder to have stabilized emulsions. In this case, the need of using more surfactant arises that have negative aspects such as increased toxic effect of the formulation. 1.3 ADVANTAGES OF SEDDS :- More consistent drug absorption, Control of delivery profile. Reduced variability including food effects.

Enhanced oral bioavailability enabling reduction in dose. High drug loading efficiency. For both liquid and solid dosage forms. These dosage forms reduce the ethical principles gastric irritation produced by tell heart, drugs.25-26. 1.4 APLLICATION OF SEDDS : Main application of this SEDDS to The Multiverse Essay increase the bioavability by increasing the heart analysis solubility of drugs. In this system we use oils for the increasing the solubility of drugs . the oils can form a layer of Internet Threats globules on tale analysis the drug so it will easily dissolve in the water.27.

1.5 Solubility and Process of Solubilization. In bioavailability of drug, solubility plays a key role because it is vital determinant of drug release and absorption. The Battle To Beat Essay. Any drug showed pharmacological response when it achieves desired concentration in systemic circulation and it is tale heart analysis depending upon solubility. Solubility is the maximum amount of solute dissolved in a certain amount of what of the medulla solvent at a specified temperature. (Shinde A. J., 2007) 1.5.1 Process of solubilization. Factors affecting solubility.

1. Particle size. 4. Other: Nature of the solute solvent, Molecular size, Polarity, Polymorphs. Absolute bioavailability and Relative bioavailability. Absolute bioavailability Intravenous dose is selected as a standard because the tale drug is assisi essay administered directly into heart analysis the systemic circulation (100% bioavailability) and avoids absorption step. Intramuscular dose can also be taken as a standard if the drug is poorly water soluble. Assisi Essay. An oral solution as reference standard has also been used in certain cases, but there are several drawbacks of using oral solution as a standard instead of an i.v. dose. Relative or comparative bioavailability. It is also termed as comparative bioavailability. It is denoted by Fr.

In contrast to absolute bioavailability; it is used to characterize absorption of a drug. Methods for enhancement of bioavailability. As per definition of bioavailability, poor permeability through the tell tale heart biomembrane owing to inadequate partition coefficient or lipophilicity or large molecular size such as that of protein or peptide drugs are poor bioavailable drugs. Both poor solubility and permeability of drug is depends upon assisi essay its physicochemical property. Biopharmaceutical Classification System (BCS) Based on intestinal permeability and analysis solubility of drugs, Amidon et al., developed Biopharmaceutical Classification System (BCS) which classify drugs into one of the four groups. Class I: These are well absorbed orally since they have neither solubility nor permeability limitation. Class II: Shows variable absorption owing to solubility limitation. Class III: also shows variable absorption owing to permeability limitation. Class IV: are poorly absorbed orally owing to both solubility and Internet Security Threats permeability limitation. There are three approaches in overcoming bioavailability problems are: It includes alteration of formulation, manufacturing process or physicochemical properties of drug devoid of tale heart analysis changing chemical structure.

It includes modification of pharmacokinetic of drug by changing its chemical structure by developing new chemical entity with desirable feature or prodrug design. By enhancing drug solubility or dissolution rate: 3. Supercritical fluid recrystallization. 4. Spray freezing into liquid. 5. Evaporative precipitation into aqueous solution. 6. Use of surfactants. 7. Use of salt forms. 8. Use of bronte governess precipitation inhibitors. 9. Tale Heart Analysis. Alteration of pH of function drug microenvironment.

10. Use of amorphous, anhydrates, solvates and metastable polymorphs. 11. Solvent deposition. 13. Tell Heart. Selective adsorption on insoluble carriers. 14. Solid solution. 15. Eutectic mixture. 16.

Solid dispersion. 17. Molecular encapsulation with cyclodextrin. By enhancing drug permeability across biomembrane. 1. Lipid technology. 3. Penetration enhancers. By enhancing drug stability. 1. Enteric coating. 3. Use of metabolism inhibitors. 1.5.3 Problems and Breakthroughs of Bioavailability Enhancement Techniques. When poor wetting properties and difficulties in processing of powders are problems reduction in particle size can not applicable in such conditions. So as to avoid such problems many other techniques have been used such as solid dispersions, permeation enhancers, cyclodextrins and nanoparticles. In fact, in some special cases, such approaches have been doing well.In the technique of reducing the size of assisi essay particles, there is affinity for agglomeration of particles due to high surface charges on small discrete particles. 1.5.4 Lipid based drug delivery. Ideal properties of Lipid based formulations. 1. Tale. It should solubilize therapeutic amounts of the bronte governess drug in tell analysis, the dosage form. 2. It should maintain adequate drug solubility over bronte the entire shelf-life of the drug product (generally 2 years) under all anticipated storage conditions.

3. Heart. It should provide adequate chemical and of nursing physical stability for analysis the drug and formulation components. 4. It must be composed of approved excipients in The Multiverse Theory, safe amounts. 5. It should adapt to the digestive processes of the GI tract such that digestion either enhances or maintains drug solubilization. 6. It should present the drug to the intestinal mucosal cells such that absorption into the cells and into tale heart analysis the systemic circulation is optimized. 2.0 NEED FOR STUDY OBJECTIVE. Oral route is the most convenient and preferable route for the administration of drugs but the The Battle to Beat Breast problems is tale heart analysis occurs due to the low solubility of drugs. About 50% of recently find drug molecules can not be formulate in the solid dosage form because of there low solubility. The need of this study was to increase the solubility of poorly soluble compound. In this formulation we can formulate a self emulsifying drug delivery system with the active ingredient telmisartain. Telmisartain practically water insoluble drugs. And having poor bioavability by the help of LSEDDS we can increase solubility of telmisartain.

3. LITRATURE SURVEY. 1. . Saritha,D. et al. (2014) Prapration a stable formulation for to Beat Breast Cancer Essay self emulsifying drug delivery systems (SEDDS) in order to enhance the solubility, release rate, and oral absorption of the poorly soluble drug, indomethacin. Tell Heart Analysis. Based on the solubility of indomethacin in to Beat, oil, surfactant and cosurfactant, pseudo-ternary phase diagrams were developed in 1:1, 1:2, 2:1, 1:3, 3:1, 4:1 ratio for SEDDS composed of labrafil, cremophor EL and transcutol P. Formulations were evaluated for drug content, phase separation, turbidimetry, zeta potential, globule size, refractive index and in vitro release. Tale. The study illustrated the potential of indomethacin SEDDS for oral administration and its biopharmaceutic performance.33. 2. Damineni,S et al (2014) developed self emulsifying drug delivery system of ibuprofen to The Multiverse Theory Essay enhance solubility, dissolution rate which may improve therapeutic performance and drug loading capacity so as to develop alternative to traditional oral formulations to improve bioavailability. In this study Labrafac, Tween 80 and PEG 200 were selected as oil, surfactant and co-surfactant respectively.

Formulation development and screening was done based on results obtained from phase diagrams and characteristics of resultant microemulsions. The developed SEDDS were evaluated for droplet size analysis, zeta potential, polydispersibility index, viscosity, refractive index, % transmittance, drug content and in vitro diffusion profiles.34. 3. Heart Analysis. Kumar,S. et al (2014) in this article we have study upper surface of SEDDS. The main advanced topic in this article is solidification process of LSEDDS and the development of solid SE dosage the last find he prolems of the assisi essay system and solve it.35. 4. Reddy,M. Tell Analysis. et al (2014) In this article we have conclude, today huge numbers of formulation avalables for the increasing poor water solubility of drugs , dissolution rate and assisi essay bioavailability of insoluble drugs. One of the promising techniques is SelfMicro Emulsifying Drug Delivery Systems (SMEDDS).

Liquid SEDDS were prepared using LLWL 1349, Labrafac PG as oils and tell cremophor EL, cremophor RH40 as surfactants and labrasol, transcutol HP as co-surfactants. The Battle To Beat Breast Cancer Essay. Prepared liquid SEDDS were evaluated for stability, particle size, zeta potential and percent transmittance. Selected liquid formulations were converted to solid SEDDS by adsorbing onto tell tale heart analysis a solid carrier Neusilin. Prepared solid SEDDS were evaluated for flow properties and in-vitro drug release studies. Results proved that prepared solid SEDDS have good flow properties and The Multiverse Theory Essay improved drug solubility and dissolution profiles (99.95%) when compared to pure efavirenz.36.

5. Amrutkar,C. et al (2014) The aim of the present study is to improve solubility and tell heart analysis hence bioavailability of Rosuvastatin calcium using self nanoemulsifying drug delivery system (SNEDDS). self emulsifying property of various oils was evaluated with suitable surfactant and co-surfactants. Ternary phase diagram was constructed based on Rosuvastatin calcium solubility analysis for optimizing the systems. The prepared formulation were evaluated for self emulsification time, dispersibility study, average globule size, Polydispersibility index (PDI). The globule size of optimized system was less than 100nm which could be an acceptable nanoemulsion range. The average globule size of the Cancer Essay selected F2 SNEDDS formulation (Capmul MCM [20%], Tween 20 [40%] and PEG 200 [40%]) was 88.01nm. In vitro drug release studies showed remarkable increase in tale heart, dissolution of F2 SNEDDS compared to marketed formulation.37. 6. . Choudhary,S.B. What Is The Of The Medulla. et al (2014) revealed formulated and characterization solid self emulsifying drug delivery system (SSEDDS) of domperidone for heart filling into soft gelatine capsule.

Pseudo ternary phase diagrams were constructed and The Multiverse liquid SEDDS formulations were prepared which consists of oleic acid, tween 20 and propylene glycol as oil phase, surfactant and cosolvent respectively. The self emulsification properties, globule size, polydispersity index of liquid SEDDS formulations were studied upon dilution with water. The solid SEDDS was prepared by spray drying method and kneading method using Aerosil 200 as solid career. The solid state characterization of the tale heart solid SEDDS was performed by ethical of nursing, SEM, DSC, and X-ray powder diffraction. Tell Tale Analysis. The results from this study demonstrate the potential use of SEDDS as a means of improving solubility, dissolution, and concomitantly the Cancer Essay bioavailability.38. 7. .Gikwad,S. et al. (2012) A reaserch on self-emulsifying drug delivery system (SEDDS) to enhance the solubility of the tell tale heart analysis poorly water-soluble drug Orlistat. These drugs can be successfully formulated for oral administration, but care needs to The Battle Cancer be taken with formulation design to ensure consistent bioavailability.

Solubility of Orlistat was evaluated in various nonaqueous carriers that included oils, surfactants, and cosurfactants. Tale. Pseudoternary phase diagrams were constructed to identify the principles of nursing self-microemulsification region. The self microemulsification properties, droplet size and thermodynamic stability of these formulations were studied upon dilution with water.38. 8. . Sachan,R. et al. (2010) To develop a formulation For the improvement of bioavailability of drugs with such properties presents one of the greatest challenges in drug formulations dissolution rate which may improve therapeutic performance and drug loading capacity so as to heart develop alternative to traditional oral formulations to improve bioavailability. In this study Labrafac, Tween 80 and PEG 200 were selected as oil, surfactant and Theory co-surfactant respectively. Tell Heart. Formulation development and screening was done based on results obtained from Security Threats phase diagrams and characteristics of resultant microemulsions.39. 9. Liu Y., et al., (2009) optimized and characterized an tell tale oridonin SMEDDS formulation using central composite design. In this study effect of concentration of oil andsurfactant and co-surfactant ratio has been studied. Study concluded that, this model is useful for optimization of SMEDDS formulation. In-vitro drug release showed that, there was increase in drug release as compared to powder formulation.40. 10.

Balakrishnan P., et al., (2009) prepared a solid SMEDDS of dexibuprofen by spray drying technique using Aerosil 200 as a solid carrier. After conversion in to solid form S-SMEDDS retains its self emulsification capacity. In-vitro drug release showed that, there was increase in Theory Essay, drug release as compared to powder formulation. In-vivo study showed that increase in bioavailability. Tell Tale Heart Analysis. Study concluded that, in the form of Solid SMEDDS it retains all characteristics of Internet liquid and it can become helpful solid dosage form.41. 11. Tell Tale Heart Analysis. Singh A. K., et al., (2009) prepared and evaluated SMEDDS of Exemestane using Capryol 90, Cremophore ELP, and Transcutol P. They compared drug release with marketed formulation in different pH. They found extensive increase of drug release than marketed formulation. They also compared absorption of drug with that of drug suspension. They found enhanced drug absorption from SMEDDS.

Study concluded that, SMEDDS have potential of enhancing solubility, absorption and governess hence bioavailability of poorly water soluble drug.42. 12. Shaji J., et al., (2008) formulated and evaluated SMEDDS of Celecoxib. They optimized formulation using 33 factorial design. Particle size was taken as response variable. Study showed that, concentration of heart different components showed prominent effect on particle size and appearance of dispersion. They found enhanced drug absorption from SMEDDS. Study concluded that, SMEDDS have potential of enhancing solubility, absorption and hence bioavailability of poorly water soluble drug.43.

13. Atef E., et al., (2008) formulated and evaluated SMEDDS of phenytoin and compared its relative bioavailability with marketed formulation. Results showed that, extensive increase in drug release form SMEDDS as compared to that of is the function marketed suspension. Also in-vivo study showed improvement in bioavailability. Study concluded that, SMEDDS is tell promising formulation to increase drug release as well as bioavailability of poorly water soluble compounds In-vitro drug release showed that, there was increase in drug release as compared to powder formulation.44. 14. Fatouros D. G., et al., (2008) studied dynamic lipolysis model for absorption of drug from assisi essay SMEDDS formulations. They also studied IVIVC with the tale help of neuro-fuzzy networks.

Study concluded that, in evaluation of SMEDDS for prediction of in-vivo behavior in-vitro dynamic lipolysis model is a possible means.45. 15. Shikov A., et al., (2008) Prepared and is the function of the medulla characterized SMEDDS of flavonoids. Prepared SMEDDS formulation was evaluated for tell self emulsification capacity, droplet size and for bioavailability. Results showed that, They found enhanced drug absorption from SMEDDS. Study concluded that, SMEDDS have potential of enhancing solubility, absorption and hence bioavailability of poorly water soluble drug. there was 2-5 fold increase in bioavailability as compared to flavonoid in powder form.46. 16.

Woo J. S., et al., (2008) developed SMEDDS of Itraconazole and studied and compared in-vivo study in The Battle Breast Cancer, human volunteers with marketed formulation having double dose. Study concluded that, there is extensive increase in tale analysis, bioavailability with reduced food effect by is the medulla, SMEDDS formulation as compared with marketed formulation. They found enhanced drug absorption from SMEDDS. Heart. Study concluded that, SMEDDS have potential of enhancing solubility, absorption and The Multiverse Essay hence bioavailability of poorly water soluble drug.47. 17. Mandawgade S. D., et al., (2008) developed SMEDDS using natural lipophile as oil phase and also compared its performance with synthetic oils. For this study beta-Artemether was used as drug.

Oil was previously evaluated for toxicity studies. Prepared SMEDDS was evaluated for globule size, in-vitro and in-vivo study. Study concluded that, performance of natural lipophiles is tale analysis better than that of Theory Essay commercially available synthetic oils hence can be used in SMEDDS as it is safe.48. 18. Yi T., et al., (2008) developed a controlled release solid SMEDDS of nimodipine using HPMC. They have prepared batches by mixing drug with HPMC and another batch by dissolving drug and tell heart HPMC in the SMEDDS. Prepared self emulsifying formulations were evaluated for surface characterization, reconstituted properties, inner physical structure and in-vitro drug release study. Study concluded that, It can be possible to formulate controlled release formulations of poorly water soluble drug by SMEDDS using high viscosity grade HPMC.49. 19.

Yi T., et al., (2008) developed a S-SMEDDS of nimodipine. Prepared S-SMEDDS was evaluated for ethical in-vitro and in-vivo absorption study. They have studied effect of dilution media and enzymatic digestion on solubilization of tell tale analysis drug .Results showed that, there is faster dissolution rate of drug from S-SMEDDS than that of assisi essay conventional tablet and enhancement of absorption as compared to liquid SMEDDS. . Prepared SMEDDS was evaluated for globule size, in-vitro and heart in-vivo study. Study concluded that, performance of Internet Security Essay natural lipophiles is better than that of tell heart analysis commercially available synthetic oils hence can be used in SMEDDS as it is safe. Of Nursing. Study concluded that, S-SMEDDS can become constructive dosage form for oral use.50. 20. Abdalla A., et al., (2008) Study concluded that, S-SMEDDS can become constructive dosage form for oral use. developed self emulsifying formulation in the form of pellets by extrusion and tell analysis spheronization technique. In. this study they found that, droplet size decreases after dilution. Study concluded that, solubilzation depend on concentration of secretions like bile salts and phospolipid.

SMEDDS can besuccessfully transformed into pellets form and can become another method to encapsulate material into hard gelatin capsule.51. 21. Lu J. L., et al., (2008) developed SMEDDS of 9NC to enhance bioavailability and anticancer effect. They prepared microemulsion of 9NC and characterized for Breast Essay citotoxicity and bioavailability study. Bioavailablity and anticancer effect have been compared with suspension of tale heart 9NC. Study concluded that, antitumor activity has been enhanced in the form of SMEDDS.52. 22. Patel D., et al., (2007) developed SMEDDS of governess Acyclovir. Prepared formulations were evaluated for different parameters.

Absorption of drug from SMEDDS was compared with plain drug solution. Results showed that, there was 3.5 fold increases in bioavailability by tell heart analysis, SMEDDS. Study concluded that, bioavailability of drug can be enhanced using SMEDDS approach. . Results showed that there were 5 fold reductions in plasma cholesterol and 4 fold reductions in plasma triglycerides when compared with reference formulation of drug suspension. Governess. Study concluded that, there was better biopharmaceutical performance of drug from SEDDS.53. 23.

Cirri M., et al., (2007), formulated oral liquid spray formulation of xibornol using SMEDDS. Prepared formulations were evaluated for rheological, stability, SAXS and in-vivo study. The study found that, SMEDDS can be used to prepare stable and effective oral liquid spray formulation. Absorption of drug from SMEDDS was compared with plain drug solution. Tell Tale Heart. Results showed that, there was 3.5 fold increases in ethical principles of nursing, bioavailability by SMEDDS. Study concluded that, bioavailability of drug can be enhanced using SMEDDS approach.54.

24. Tell Heart. Patil P., et al., (2007) formulated a SEDDS for simvastatin. Prepared SEDDS was evaluated for ethical principles turbidometric analysis, particle size, in-vitro drug diffusion and in-vivo study in rat. Results showed that there were 5 fold reductions in plasma cholesterol and 4 fold reductions in plasma triglycerides when compared with reference formulation of tell tale drug suspension. Study concluded that, there was better biopharmaceutical performance of drug from SEDDS.55. 25. Patel A. R., et al., (2007) formulated and evaluated SMEDDS of Internet Security fenofibrate. From solubility study of drug in different components oil, surfactant and co-surfactant were selected and pseudo ternary phase diagram were constructed. Tell Tale. From this SMEDDS were prepared and evaluated for thermodynamic, dissolution, stability study and lipid lowering capacity. Study concluded that, SMEDDS can improve dissolution rate and hence bioavailability of drug which become substitute for oral drug delivery system. Internet Security Threats Essay. Study concluded that, there was better biopharmaceutical performance of drug from tale SEDDS.56.

26. Assisi Essay. Shen H., et al., (2006) prepared and evaluated SMEDDS of atorvastatin using Labrafil, PEG and Cremophor RH40. From solubility study of drug in different components oil, surfactant and tell analysis co-surfactant were selected and The Battle Breast Essay pseudo ternary phase diagram were constructed. Tale. SMEDDS capsule of atorvastatin were prepared and drug release were studied and compared with conventional tablet. Results showed that release of drug was much higher from SMEDDS capsule than that of tablet. Study concluded that, bioavailability of drug can be enhanced using SMEDDS capsule than conventional tablet. controlled release of drug can be obtained from lipid formulations in tablet dosage form.57.

27. Boonme P., et al., (2006) characterized colloidal state in microemulsion system. Ethical Principles. They constructed pseudo ternary phase diagram by water titration method. different process parameters affect dissolution rate of drug from tell tale heart tablet. Of The. Study concluded that, controlled release of drug can be obtained from lipid formulations in tablet dosage form. Different samples were prepared by keeping surfactant concentration of 45 % and by varying proportion of water.

Prepared samples were evaluated for appearance, viscosity, conductivity, DSC, SEM and NMR. Heart Analysis. Study concluded that, if composition has 15 % of water, it contain reverse micelles, W/O emulsion obtain if it contain 15-30 % of assisi essay water and it gives O/W emulsion of it contain more than 35 % of water.58 28. Tell Tale. Nazzal S., et al., (2006) evaluated different process parameters which affect release of drug from bronte governess SNEDDS in tablet dosage form. Heart Analysis. Solid preparation was prepared to study absorption of Theory Essay drug in rat and dog. Prepared tablets were evaluated for dissolution and tell tale heart analysis stability studies. Results showed that, different process parameters affect dissolution rate of drug from tablet. Study concluded that, controlled release of drug can be obtained from ethical principles lipid formulations in tablet dosage form.59 29.

Wu W., et al., (2006) prepared SMEDDS of silymarin. From solubility study of drug Tween 80, ethyl alcohol and tell ethyl linoleate were selected as formulation components Solid preparation was prepared to study absorption of drug in governess, rat and tale heart dog. Assisi Essay. Results showedthat Florite RE gives more absorption of drug both in rat and dog. Analysis. Results showed that, there is assisi essay increase in particle size as increase in drug loading in formulation. Drug release was much higher than that of crude drug powder. Study concluded that by using SMEDDS bioavailability of silymarin can be enhanced.60 30.

Ito Y., et al., (2005) prepared solid formulation of gentamicin using different adsorbents and surfactant to enhance absorption of tell tale analysis drug. Florite RE, Neusilin US2 and Sylysia 320 were used as adsorbents and bronte Labrasol was used as surfactant. Prepared formulation was evaluated for particle size, drug release and bioavailability study. Results showed that, there is increase in particle size as increase in drug loading in formulation Study concluded that by using adsorbent and surfactant system oral solid formulations can be prepared so as to increase absorption of poorly absorbable drug.61 31. Sha X., et al., (2005) studied effect of charge and dilution on TEER and permeability of mannitol by tale heart analysis, formulating SMEDDS using Labrasol and also studied effect of dilution of surfactant on ZO-1 and F-actin. Is The Function Medulla. Study concluded that, SMEDDS of both positive and negative charge containing Labrasol are capable of tell heart enhancing the paracellular tramsport of mannitol across Caco-2 cell at different dilutions. , there was significant increase in what is the function of the, rate and extent of absorption of drug as compared to capsule. Tell Tale Heart Analysis. It was also found that, there was 1.5 fold increases in bioavailability than tablet. Study concluded that, SMEDDS can be beneficial for oral delivery of poorly water soluble drug such as simvastatin.62 32. . Subramanian N., et al., (2004) developed and optimized SMEDDS of Celecoxib using simplex lattice mixture design. Prepared SMEDDS were evaluated for The Multiverse Theory Essay Clarity, solubility, in-vitro dissolution and in-vivo study. Results showed thatRelative bioavailability with capsule was found to tale heart be 132 %. Study concluded that, prepared formulation will reduce variability in absorption and rate and assisi essay gives rapid onset of action of drug.

It was also found that, there was 1.5 fold increases in bioavailability than tablet. Study concluded that, SMEDDS can be beneficial for oral delivery of poorly water soluble drug such as simvastatin.63 33. Tale Heart Analysis. Kang B. K., et al., (2004) prepared SMEDDS of simvastatin using Carpryol 90, Cremophor EL and Carbitol. Prepared formulations were evaluated for Sustained drug release was achieved by using Silicon dioxide as gelling agent which retarded release of drug, in-vitro dissolution study and bioavailability study. Results showed that, in-vitro of drug was much higher that that of conventional tablet. It was also found that, there was 1.5 fold increases in The Multiverse, bioavailability than tablet. Study concluded that, SMEDDS can be beneficial for oral delivery of poorly water soluble drug such as simvastatin.64 34. Tell Analysis. Patil P., et al., (2004) formulated a gelled SEDDS of ketoprofen using Captex 200, Tween 80 and Capmul MCM.

Sustained drug release was achieved by using Silicon dioxide as gelling agent which retarded release of drug. Study concluded that, as concentration of gelling agent increases it increase droplet size of assisi essay emulsion formed which helps in slowing drug diffusion. It was also found that, as concentration of co-surfactant increase drug release from dosage form also increases.65 35. Tell Tale Heart. Holm R., et al., (2003) importance of this examined oral absorption and to Beat Breast Cancer Essay lymphatic transport of halofantrine in SMEDDS containing triglycerides, Sustained drug release was achieved by using Silicon dioxide as gelling agent which retarded release of drug. Maisine-35-1 and Cremophor EL. Study verified that, after administration of halofantrine in SMEDDS lymphatic transport and absorption was affected. Study concluded that, by using differentstructure of triglycerides it is achievable to enhance lymphatic transport of tell tale heart analysis compound without affecting its availability.66 36. Itoh K., et al., (2002) the Theory Essay aim of this present researched topic improved solubility of N-4472 by formulating self-micro emulsifying system using Gelucirei??i?? 44/14, HCO and SDS. Tale Heart Analysis. Study concluded that, formulate sedds to enhance the bioavability and formed stable microemulsion droplets. SDS showed vital role in stability of microemulsion droplets.67 37.

Agarwal V., et al., (2000) investigated effect griseofulvin SMEDDS addition to assisi essay silica and silicate on flow properties and tell tale heart in-vitro drug release. Results showed that, increase in surface area increases dissolution of assisi essay drug. Study concluded that, nature and amount of adsorbent affect flow properties and dissolution of drug in SMEDDS. In-vitro drug release showed that, there was increase in drug release as compared to powder formulation.68 38. Kim H. J., et al., (2000) developed SMEDDS of idebenone using Labrafil 2609, Labrasol. Transcutol and tell tale analysis Plurol oleique WL1173 so as to enhance bioavailability by the increasing the assisi essay solubility of the poorly water solublr drug. Results showed that, in-vitro dissolution rate of drug were increased 2 folds than that of heart analysis tablet. Study concluded that, SMEDDS can be used as substitute for principles traditional oral formulations to enhance bioavailability of idebenone.69 39. Chen G. L., et al., (1996) the heart importance of this present researched study was validated bioanalytical method for determination of Verapamil from plasma by HPLC for pharmacokinetic study of Verapamil. They also studied sensitivity, specificity, linearity, accuracy, precision and sample stability of method. For the purpose of sedds evaluation.70 40.

Shah N. H., et al., (1994) the The Battle Breast Cancer aim of this study was investigated emulsification efficiency of polyglycolyzed glycerides (PGG) and polyethylene glycol (PEG). They prepared SEDDS using different concentrations of tell PGG as emulsifiers,oils and is the function different type of surfactant and co-surfactant. Neobee M5 and tell tale analysis Peanut Oil were selected as oil. Drug having good solubility in oil was selected for this study. Study showed that, PGG can be used as emulsifier for preparation of SEDDS.71 MATERIAL METHOD 4. MATERIAL AND METHOD 4.1 MATERIALS Table 4.1: List of bronte governess materials with sources S. No. Materials Source 1. Telmisartan Skymap Pharmaceuticals, Roorie 2. Tween 80 Loba chemic laboratory regents Mumbai 3. PEG 400 Nasco laboratory 4. Methanol Loba chemic laboratory regents Mumbai 5. Hydrochloric acid Loba chemic laboratory regents Mumbai 6. Orange oil Burgone laboratory Mumbai Table 4.2: List of equipments with make S. No. Tell. Equipment Make 1. Breast. Analytical balance Fuji electronic balance 2. Tale Heart Analysis. Melting point apparatus Jyoti digital auto melting apparatus 3. UV Spectrophotometer Jasco japan-v630 4. Of Nursing. Dissolution apparatus Jyoti standard dissolution apparatus 5. FTIR Jasco-japan FT/IR/4100 7. Tell Tale Heart Analysis. mixing Jyoti lab gwl. INDIA 8. Hot air oven Jyoti lab gwl.

INDIA 9. Water bath Jyoti lab gwl.INDIA 4.1.1 Drug profile: Telmisartan72 Telmisartan is 4-[[4-Methyl-6-(1-methyl-1H-benzimidazol-2-yl)-2-propyl-1H-benzimidazol-1- yl]methyl]biphenyl-2-carboxylic acid. Structural formula Figure 3.1: Structure of telmisartan Molecular formula- C33H30N4O2 Molecular weight- 514.6 Definition 4-[[4-Methyl-6-(1-methyl-1H-benzimidazol-2-yl)-2-propyl-1H-benzimidazol-1- yl]methyl]biphenyl-2-carboxylic acid. Content: 99.0 per cent to 101.0 per cent (dried substance). Category: Antihypertensive. Dose: 20 to 80 mg. Half life: 24 hrs. Appearance: White or slightly yellowish, crystalline powder. Solubility: Practically insoluble in water, slightly soluble in methanol, sparingly soluble in methylene chloride.

It dissolves in 1 M sodium hydroxide. It exhibits polymorphism. Melting point: 261 263oC. Storage: it should be stored at room temperature (15 30 i??i??C), away from moisture and light. Principles Of Nursing. Mechanism of action: It is an angiotensin II receptor antagonist. Telmisartan exhibits high affinity with the angiotensin II type one receptors in adrenal gland and in vascular smooth muscles. It works by tell analysis, binding to the angiotensin II receptor. Assisi Essay. It inhibits the action of angiotensin which is a vasoconstrictor.

Angiotensin also stimulates the synthesis and release of tale analysis aldosterone. By blocking the principles of nursing vasoconstrictor effect of the angiotensin and tale heart blocking the aldosterone, Telmisartan reduces the systemic vascular resistance. Pharmacokinetics: Absorption: After the oral administration peak concentrations (Cmax) of telmisartan are attained in Theory, 0.5 to 1 hour. Ingestion with food slightly decreases the bioavailability of tell tale analysis Telmisartan. Absolute bioavailability is dose dependent. At 40 and 160 mg the bioavailability was found to be 42% and 58%, respectively. Distribution: Binding with plasma proteins is constant with the recommend doses. It is highly binding with the plasma proteins (more than 99.5 %).

It has a volume of distribution of around 500 L. Metabolism: Telmisartan is metabolized by forming a pharmacologically inactive compound acyl glucuronide by ethical principles, conjugation. The only identifiable compound in the human plasma and urine is the glucuronide. Elimination: Telmisartan has a half life of 24 hour and total plasma clearance of more than 800 mL/min. More than 97% of the analysis orally/IV administered telmisartan is The Battle to Beat Cancer eliminated in tell, the feces via biliary excretion, unchanged. Uses: It is used to treat high blood pressure (hypertension). Adverse effects: The common reported adverse effects of telmisartan are upper respiratory tract infection (URTI) (7%), Back pain (3%), Diarrhea (3%), Myalgia (3%), and Sinusitis (3%).

Some rare adverse effects (1%) are abnormal ECG, anemia, angina, angioedema, bradycardia, eczema, epistaxis, gout, and Theory hypercholesterolemia. Tell Tale Analysis. Drug interactions: Telmisartan has found interacting with several drugs such as, benazepril, benazepril, benazepril, benazepril, benazepril, and benazepril etc. What Is The Function. Caution is advised when combination will be used. Dosage forms: It is tale commonly used in the form of tablets of 20, 40, and 80 mg. 4.1.2 TWEEN 80 72-73 Chemical Name: Tween 80 Molecular Formula: C24H44O6 Formula Weight: 428.600006103516 Tween 80 Property Boiling point- 100i??i??C. Dencity 1.08 g/mL at 20 i??i??C. Vapour pressure- 230 i??i??F. storage temp. : Store at RT. From- viscous liquid. Water Solubility : 5-10 g/100 mL at 23 i??i??C. EPA Substance Registry System: Sorbitan, mono-(9Z)-9-octadecenoate, poly(oxy-1,2-ethanediyl) derivs.(9005-65-6)

Tween 80 Chemical Properties,Usage,Production. Yellow to amber liquid. Amber-colored viscous liquid. pH (5% aqueous solution) 5-7. Faint odor and bitter taste. Air Water Reactions.

Tween 80 is incompatible with strong alkalis and oxidizers. Tween 80 is probably combustible. 4.1.3 ORANGE OIL 72-73:- It was the important and essincial oil can be produse by the cells in the fruits of oranges. They can also be extracted by orange juse it will compose mostely d-limonene. That will be extract to The Multiverse Theory Essay the oil by tell tale analysis, distillation. Odour- fresh and tangy smell, Coloue- yellow to Internet Threats orange in color. Self life- approximately 6 months.

Origin of Sweet orange oil. This evergreen tree has dark green leaves and tale white flowers and assisi essay bright orange round fruit with roughish skin. Analysis. The trees are native to China, but are now cultivated extensively in America. 1. It can be used many Curacao type liqueurs. 2. for the flavoring of food. 3. The Battle Breast. drink and confectionery. 4. when added to furniture polish. 5. helps to protect against tale heart, damage from insects. The orange oil are extracted by cold-pressing and yields 0.3 -0.5 %. It can also use for Theory Essay the medicinal perpose that will gives several therapeutic actions are antiseptic, anti-depressant, antispasmodic, anti-inflammatory, carminative, diuretic, cholagogue, sedative and tonic. The main chemical components of orange oil are a-pinene, sabinene, myrcene, limonene, linalool, citronellal, neral and geranial.

1. It is a safe non-toxic, non-irritant and non-sensitizing oil, 2. yet care must be taken with it since it can have a phototoxic effect. 3. It should therefore preferably not be applied before going out into sunlight for prolonged periods. Iupac name polyethylene glycol. 90.0 cst at 25 i??i??C, 7.3 cst at 99 i??i??C.

PEG 400 properties. 1. (polyethylene glycol 400) is a low-molecular-weight grade of polyethylene glycol. 2. It is a clear, 4. Tell Heart. viscous liquid. 5. Due in ethical of nursing, part to tale analysis its low toxicity, PEG 400 is widely used in a variety of pharmaceutical formulations. 1. PEG 400 is soluble in water, acetone, alcohols, benzene, glycerin, glycols, and aromatic hydrocarbons, and is slightly soluble in aliphatic hydrocarbons.

2. PEG 400 is strongly hydrophilic. 3. The partition coefficient of The Multiverse Theory PEG 400 between hexane and water is 0.000015 (log ), indicating that when PEG 400 is mixed with water and hexane, 4. there are only 15 parts of PEG 400 in the hexane layer per 1 million parts of PEG 400 in the water layer.[1] PEG 400 is soluble in water, acetone, alcohols, benzene, glycerin, glycols, and heart analysis aromatic hydrocarbons, and bronte governess is slightly soluble in aliphatic hydrocarbons. 4.2 Preformulation studies 72,73,74,75. To develop a safe, stable and therapeutically effective dosage form, preformulation studies are necessary to perform. The preformulation studies, which were performed in this project, include identification of drug, melting point analysis, solubility analysis, and quantitative estimation of drug.

4.2.1 Identification tests. Physical appearance: The drug was white, odorless crystalline powder. Melting point analysis: Melting point of telmisartan was determined by tell tale analysis, capillary method using melting point apparatus (Rolex- Digital melting point apparatus). FTIR study: Drug sample was vacuum dried for 12 h before IR studies. IR spectra of pure telmisartan, PEG 4000, mannitol and solid dispersions of telmisartan were obtained by a Shimadzu IR Prestige-21 FT-IR spectrophotometer using KBr pellets. The scanning range used was 4000 to 400cm-1.

The observed peaks were reported for functional groups. 4.2.2 Loss on drying73-74. It was determined on 1 g drug by drying it in a hot air oven at 105oC. To Beat. The weight was determined at 15 min intervals till the difference was not more than 0.5 mg. Tell Tale Heart. The total difference in weight should not be more than 0.5%. 4.2.3 Determination of max 73. Accurately weighed sample of 10 mg of telmisartan was dissolved in 50 mL of methanol in The Multiverse Essay, a 100 mL volumetric flask and then the volume was made up to tell heart 100 mL with methanol.

Then, 1 mL of this stock solution was pipetted into a 10 mL volumetric flask and volume was made up to the 10 mL mark with methanol. Theory Essay. The resulting solution was scanned between 200-600 nm using UV/Vis double beam spectrophotometer (UV-1700, Shimadzu, Japan). The same procedure was followed to determine the max in HCl buffer (pH 1.2). The prepared solution was scanned between 200-600 nm using UV/Vis double beam spectrophotometer (UV-1700, Shimadzu). To determine max in tell heart, water, accurately weighed 10 mg sample of telmisartan was dissolved in 50 mL of methanol in a 100 mL volumetric flask and volume was made up to 100 mL with methanol. Then, 1 mL of what is the of the medulla this stock solution was pipetted into a 10 mL volumetric flask and tell tale heart analysis volume made up to the 10 mL mark with distilled water. The resulting solution was scanned between 200-600 nm using UV/Vis double beam spectrophotometer (UV-1700, Shimadzu, Japan). 4.2.4 Quantitative estimation of drug73-74. Drug was estimated in the range of 3-15 mcg/mL for telmisartan in water (pH 7.0), HCl buffer (pH 1.2) and methanol.

Preparation of HCl buffer (pH 1.2): 50 mL of 0.2 M KCl was added in a 200 mL volumetric flask then 85 mL of HCl solution (0.2 M) was added in the flask and to Beat Cancer volume was adjusted to 200 mL with distilled water32. 4.2.5 Construction of calibration curve of telmisarta73. Preparation of calibration curve in methanol: The 25mg of accurately weighed telmisartan was dissolved in 25 mL of methanol to give standard solution (1000 i??i??g/mL). From this standard solution, 3 mL was pipetted out and volume was made up to 100 mL with methanol referred as stock solution of concentration 30i??i??g/ mL. Aliquots of 1 mL, 2 mL, 3 mL, 4 mL and 5 mL of stock solution were pipetted out into separate 10 mL volumetric flask. The volume was made up to the mark with methanol.

This results in tell tale heart, samples of 3, 6, 9, 12 and The Battle to Beat Cancer Essay 15 g/mL concentration, respectively. The absorbance of prepared solution of telmisartan in methanol was measured at tale heart, 296.5 nm in Shimadzu UV-1700 spectrophotometer against an appropriate blank. Preparation of calibration curve in HCl buffer (pH 1.2): Exact procedure was followed as described above by using HCl buffer (pH 1.2) instead of methanol. The absorbance was recorded at what function of the medulla, 296 nm. 4.2.6. solublity of telmisartain in heart, different medium. Solubility of telmisartain was determine in the different medium by heand shaking method. 3.3 Formulation 76. 4.3.1 identification of microemulsion region : Determine solubility of telmisartain in different -2 medium then select three medium orange oil as oil, PEG 400 as surfactant and tween 80 as co-surfactant. Internet Security Threats. Micro-emulsion region was identify by constructing pseudo ternary phase diagram with the help of different proportion of surfactant and co-surfactant (1:1, 2:1, 3:1). Tell. They are mix with oils at different proportion (1:9, 2:8, 3:7, 4:6, 5:5, 6:4, 7:3, 8:2, 9:1) and the complete mixture was titrate with water and noted the governess equbliurem point.

At which point the mixture will show clear. 4.3.2 preparation of liquid SMEDDS: Due to the higher microemulsion region in the 3:1 proportion (surfactant:co-surfctant) was selected for the preparation of LSEDDS. 1. Required amount of PEG 400 and tween 80 was take and mix with the heart help of stirrer until they compatibly mix. 2. Aquaretly weight telmisartain and ethical principles of nursing take required amount of orange oil and mix il. 3. Drug mixture place on water bath until drug completely dissolve in oil. 4. Both the mixture are mix togather on the magnatic stirrer untill they are compleately mix and tell form a isotropic mixture. 5. Store in the glass bottle.

Table 4.3 chemical requirements. Orange oil 50 ml. Tween 80 12.5 ml. Telmisartain 2000 mg. 4.4 CHARACTERIZATION :76-77. 4.4.1 stability study :76. heating cooling cycle: for the Internet Essay stability study of tell analysis LSEDDS pass six cycle between hot and cool temperature (40c-450c) with storing not less then 48hrs at each temp. not seen any type of phase sapration. centrifugation test: After passing heating cooling cycle it would be pass with centrifugation test. The Battle To Beat Breast. The sample of LSEDDS placed in centrifuge for 30min and show any type of precipitation. If not seen it would be go to the next stability test. freeze thaw cycle: This test is again at cool and hot temperature (-210C to +250C) 48 hrs at each temp. If the LSEDDS pass all the tell heart stability parameter means the system becomes stable. 4.4.2 cloud point measurement : 76-77. Liquid SMEDDS was diluted with distilled water at 250 times LSEDDS : distill water(1:250), placed in a water bath and its temperature was increased slowely-2.

Cloud point was measured as the of nursing temperature at which there was a sudden appearance of cloudiness visually. 4.4.3 solubility test .77-78. Solubility of LSEDDS was determine at buffer solution at 1.2ph, 7.4ph, and methanol by using standard paddle type dissolution test apparatus. Preparation of analysis HCl buffer (pH 1.2): 50 mL of 0.2 M KCl was added in a 200 mL volumetric flask then 85 mL of Theory Essay HCl solution (0.2 M) was added in tell tale analysis, the flask and volume was adjusted to 200 mL with distilled water. Buffer pH 7.4: Mix 50 mI of solution containing 1.944 per cent w/v ofsodium acetate and is the of the 2.946 per cent w/v of barbitone sodium with 50.5 mI of tale analysis 0.1 M hydrochloric acid, add 20 mI of an 8.5 per Internet Threats, cent w/v solution of sodium chloride and tell dilute with water to 250 mI.

4.4.4 efficiency of self emulsification :76-77. Using USP- type-II dissolution test apparatus (Veego VDA-8DR). 1 mL of principles Liquid SMEDDS was added drop wise to 200 ml of 0.1 N HCl at 37i??i??C. agitate using by tale analysis, using standard stainless at rotating paddle at 60 rpm. Governess. SMEDDS assessed visually according to the rate of tale analysis emulsification and final appearance of the emulsion. 4.4.5 Robustness to dilution :76. it can be studied by Theory Essay, by diluting LSEDDS at different concentration with distill wate. 1. Prepare HCL buffer solution PH 7.4, PH 1.2. 2. Prepare dilution with both the solution at following concentration. 3. Store for 12 hrs.

4. Observe any type of phase saperation or pracipation. 4.4.6 % transmittance :76. For the determination of % transmittance take. 1. 1ml of LSEDDS and diluted till 100ml with distilled water. 2. Scan this sample in the uv spectroscopy. 3. observe any type of turbidity and % transmittance. 4.4.7 Dye solubility test : 76. This test can be perform for the conformation of oil in water nature of LSEDDS by observing sopntenious dispersion. 1. Tell Tale. Take water soluble dye and sufficient quantity of assisi essay LSEDDS. 2. Rapidly incorporate dye into the system. 4.4.8. in vitro drug release:76-77.

In vitro dissolution study of LSEDDS using type -2 dissolution test apparatus in buffer solution ph 1.2, ph 7.4 at 370 c. Drug release in buffer solution at 1.2 PH :- 1. Prepare buffer solution 1.2 PH by the help of indian pharmacopeia. 2. Tell Analysis. Fill in the type-2 dissolution test apparatus upto 900ml . 3. Palce 2ml sapmle of bronte LSEDDS in the apparatus. Tale. Start the assumbaly. 4. Take sample after regular interwal. 5 min, 10 min,15 min,30 min,45 min,60 min,90 min,120 min. 5. The all sample was filtered with whatmant filter paper.

And dilute upto 10ml. 6. If there concentration is high then take again 1ml to all the governess samples and tell tale analysis and dilute again upto 10ml. 7. The sample was scan into the uv spectroscopy at 296nm. Drug release in ethical of nursing, buffer solution at 7.4 PH :- 1. Prepare buffer solution 7.4 PH by the help of indian pharmacopeia. 2. Fill in analysis, the type-2 dissolution test apparatus upto 900ml . 3. Palce 2ml sapmle of LSEDDS in the apparatus. Start the assumbaly. 4. Bronte. Take sample after regular interwal. 5 min, 10 min,15 min,30 min,45 min,60 min,90 min,120 min.

5. The all sample was filtered with whatmant filter paper. And dilute upto 10ml. 6. If there concentration is high then take again 1ml to all the heart samples and Internet Security Essay and dilute again upto 10ml. 7. The sample was scan into the uv spectroscopy at tell tale, 296nm. 4.4.9 drug contant:76-77-78-79. drug content of LSEDDS should be determine by diluting 1 ml sample of LSEDDS with distill water.

Take there absorbance in uv-spectroscopy at296nm. 1. Take 1ml sample of LSEDDS and dilute with distill water upto 100ml. 2. If the concentration of sample was high then furthers 1ml sample dilute with distill water upto 10ml. 3. Governess. Scan this sample in uv-spactroscopy. 4. Calculate there percentage by the help of tell heart analysis leaner line equation. RESULT AND DISCUSSION. Table 5.1: Melting point of telmisartan.

S. Bronte. No. Melting point Result. 5.1 LOSS ON DRYING: The results were within the acceptable limit which is 0.5%. Table 5.2: Loss on drying. S.No. Time (min) Weight (mg) Difference in weight (mg)

Total difference 2.9. 5.2 FTIR spectroscopy: FT-IR spectra of pure drug telmisartan and its solid dispersion which are shown in figure 7.1 and heart analysis 7.4. There was not any significant interaction found between drug and carriers which confirms the stability of drug in the formulation. Table 5.3: Major peaks observed in FTIR spectrum of telmisartan. S. No.

Standard peak Observed peak Comments. 1. Principles. 3059.1cm-1 3080 cm-1 C-H stretching (aromatic) 2. 2958.8-2868.15 cm-1 2870-2738.92 cm-1 C-H stretching (aliphatic) 3. 1697.36 cm-1 1687.71 cm-1 C=O stretching. 5. 1521.84-1458.18 cm-1 1462.04 C=C stretching ring. Figure 5.1: FT-IR spectra of tell analysis pure telmisartan.

5.4 LEMDA MAX OF TELMISARTAIN IN DIFFERENT SOLVENT SYSTEM : Table 5.4: Solvent systems, their parameters and values. S.No. Solvent system Parameters Values. 1. Methanol i??i??max 296.5 nm. Beers law range 3 15 mcg/mL. Regression line equation y = 0.050x + 0.007. Regression coefficient (R2) 0.999. 2. Buffer 7.4 i??i??max 298 nm. Beers law range 3 15 mcg/mL. Regression line equation y = 0.043x + 0.004.

Regression coefficient (R2) 0.999. 3. The Multiverse Theory Essay. HCl buffer (pH 1.2) i??i??max 296 nm. Beers law range 3 15 mcg/mL. Regression line equation y = 0.046x + 0.007. Regression coefficient (R2) 0.999. 5.5 CALIBRATION CURVE OF TELMISARTAN IN DIFFERENT SOLVENT SYSTEM. Table 5.5: Calibration curve of tell telmisartan in HCl buffer pH 7.4 and HCl buffer pH 1.2 at max 298 nm and Internet Security Essay 296 respectively. S.No. Concentration (i??i??g/mL) HCl buffer pH 7.4 HCl buffer pH 1.2. Absorbance Regressed Absorbance Absorbance Regressed Absorbance.

2. 3 0.139 0.133 0.153 0.145. 3. 6 0.270 0.262 0.294 0.283. 4. 9 0.401 0.391 0.423 0.421. 5. 12 0.537 0.520 0.567 0.559. 6. 15 0.657 0.649 0.706 0.697. S.No.

Concentration (i??i??g/mL) Methanol. Absorbance Regressed Absorbance. Table 5.6: Calibration curve of telmisartan in tell analysis, methanol at max 296.5 nm. Figure 5.2: Calibration curve of telmisartan in buffer 7.4 ph at 298 nm. Figure 5.3: Calibration curve of telmisartan in assisi essay, HCl buffer pH 1.2 at 296 nm. Figure 5.4: Calibration curve of telmisartan in methanol at tell heart, 296.5 nm.

5.6 SOLUBILITY OF TELMISARTAIN : Table 5.7: solubility of telmisartain in different medium. S.NO. MEDIUM SOLUBILITY. 1. Water Insoluble. 2. Hcl Springly soluble. 3. Security Threats Essay. Methanol soluble. 5. Heart. PEG400 Soluble. 6. Tween 80 Springly soluble.

7. Tween 20 Springly soluble. 8. Span 80 Springly soluble. 5.7 IDENTIFICATION OF MICRO-EMULSION REGION BY PREPAPE PSUDO TERATORY PHASE DIGRAM. In this formulation preportion of surfactant and co surfactant is 1:1. Table 5.8: identification of micro-emulsion region. SMIX : OIL END POINT. In this formulation preportion of surfactant and co surfactant is assisi essay 2:1. Table 5.9: identification of micro-emulsion region.

SMIX : OIL END POINT. In this formulation preportion of surfactant and co surfactant is heart 3:1. Table 5.10: identification of bronte micro-emulsion region. Smix : OIL END POINT. Result- Best micromulsion was found to be In formulation 3 at 5:5 proportion of oil and heart analysis mixture of assisi essay surfactant and co-surfactant denoted as smi. 5.8 FORMULATION OF LIQUID-SELF EMULSIFYING DRUG DELIVERY SYSTEM (LSEDDS). 5.8.1 chemical requirement: Table 5.11: chemicals requirements . Orange oil 50 ml. Tween 80 12.5 ml. Telmisartain 2000 mg/2gm. 5.9 EVALUATION OF LSEDDS.

5.9.1 stability study. Physical stability was important parameter in the emulsion system it can be affected the performance of the system, it can be occurs due to the precipitation of drug. Due to the poor stability of system bioavability of drug also affected. For the thermodynamic stability study of LSEDDS was perform by tell tale, following perameater. 1. Heating cooling cycle.

2. Centrifugation test. 3. Freeze thaw cycle. When system can not show any type of phase separation during heating cooling cycle then syatem can be tested in the centrifugation for Security Threats the drug pricipation then apply freeze thaw cycle for the stress test. heating cooling cycle : 40c No separation. 450c No separation. 40c No separation. 450c No separation. 40c No separation. 450c No separation. 40c No separation.

450c No separation. 40c No separation. 450c No separation. 40c No separation. 450c No separation. Table 5.12: six cycle of heating cooling temp. Result not seen any type of tell tale phase saperation. Centrifugation test:

Result- LSEDDS was centrifuge for 30 min there was not seen any type of The Multiverse Essay precipitation and phase saperation. freeze thaw cycle. Table 5.13: three cycle of tale heart -210c to The Multiverse Theory Essay +250c. Cool temp. No change.

Hot temp. No change. Cool temp. No change. Hot temp. No change. Cool temp. No change. Hot temp. No change. 5.9.2 cloud point measurement. Table 5.14: Cloud point. Sample Cloud point.

Result- cloud point of this emulsion system was found to be more then 860c. which indicates that our LSEDDS was stable at the physiological temperature without any risk of phase separation. 5.9.3 solubility study: Table 5.15: solubility of LSEDDS. Medium Solubility time. Buffer solution PH 1.2 Less than 5min. Buffer solution PH Less than 5min. 0.1 N HCL Less than 5min.

Result solubility of this system was found to be less than 5min which indicates that the formulation also use in the sustain release drug delivery system with maximum bioavability. 5.9.4 Efficiency of tell self-emulsification. Sample Efficiency of LSEDDS. 1 Less than 1min. 2 Less than 1min. 3 Less than 1min. Result this system rapidly form micro emulsion with in 1min it was clear and appearance was slightly blush. 5.9.5 Robustness to dilution : Table 5.15: dilution with different solvents. Concentration Water Buffer solution.

PH 1.2 Buffer solution. 50 times No change No change No change. 100 times No change No change No change. 500 times No change No change No change. 1000 times No change No change No change. Result in the robustness dilution not seen any type of phase separation and pracipation. Result- % trasmittance of this system was found to be 93.5. 5.9.7. dye solubility test.

Result- type of emulsion was conform by assisi essay, using dye solubility test in which a water soluble colourfull dye rapid incorporate in the LSEDDS and tell tale analysis observe. The Multiverse Theory. Which indicates that the continuous phase in this system is water. so it was conform that the analysis LSEDDS was o/w micro emulsion. 5.9.8 in-vitro drug release profile. drug release in assisi essay, buffer solution PH1.2. Table 5.16 in-vitro drug release of SEDDS. % cumulative drug release. Plain drug LSEDDS. 10 min 7.35 42.43. 15 min 11.63 61.36. 30 min 1.83 75.45.

45 min 18.64 83.33. 60 min 23.31 89.02. 90 min 27.15 95.26. 120 min 29.48 95.56. Figure 7.4 commulative % drug release of SEDDS and plain telmisartain in PH 1.2. drug release in buffer solution PH 7.4.

Table 5.17 in-vitro drug release of SEDDS. % cumulative drug release. Plain drug LSEDDS. 10 min 11.38 47.39. 15 min 14.92 54.43. 30 min 19.61 73.13. 45 min 24.48 81.68. 60 min 28.29 90.83. 90 min 32.62 96.54. 120 min 33.46 98.12.

Figure 7.6 % commulative drug release of tell tale heart LSEDDS and plan telmisartain in PH 7.4. 5.9.9 drug content estimation. Table 5.18 drug content: The oral route is the bronte governess most preferred method of administration of drugs. Tell Analysis. Unfortunately, this route is not possible for 50% of currently marketed drug compounds due to Security Threats their low solubility in water and low oral bioavailability. We study that self-emulsifying drug delivery system (SEDDS) can be used for the improvement of bioavailability of the analysis drug. In the preparation of this system containing with telmisartain as active pharmaceutical ingredient. To increase bioavailability solubility of this drug. Due to poor solubility of telmisartain it cannot be formulate in the oral drug delivery system. But with the help of LSEDDS its possible to principles give telmisartain via oral drug delivery system.

After the complete study of LSEDDS we conclude that the system was very useful for the active drug molecules having poor solubility. 1. Yamamoto, J. and H. Tanaka, prepare neomatic phase in the liquid micro-emulsion. Nature (London), 2001. 409(6818): p. 321-325. 2. Porter, C.J.H., N.L. Trevaskis, and tell tale heart W.N. Charman, Lipids and lipid-based formulations: for the optimization of drug delivery by oral route lipophilic drug. Nature Reviews Drug Discovery, 2007. 6(3): p. 231-248.

3. Humberstone, A.J. and W.N. Charman, the oral drug delivery of Internet poorly water soluble drugs. By forming a lipid based drug delivery system Advanced Drug Delivery Reviews, 1997. 25(1): p. 103-128. 4. Kommuru, T.R., et al., Self-emulsifying drug delivery systems (SEDDS) of coenzyme Q10: formulation development and bioavailability assessment By forming a lipid based drug delivery system Advanced Drug Delivery. Int J Pharm, 2001. 212(2): p. Heart. 233-46. 5. Neslihan Gursoy, R. and S. Benita, Self-emulsifying drug delivery systems (SEDDS) for improved bioavability of to Beat Essay poorly water soluble drug. Biomedicine Pharmacotherapy, 2004. 58(3): p. 173-182.

6. Hauss, D.J., et al., prepare lipid based drug delivery system for poorly water soluble drug LTB4 inhibito to enhance there solubility as well as bioavability. Journal of tell tale analysis Pharmaceutical Sciences, 1998. 87(2): p. The Multiverse Theory. 164-169. 7. Gao, P., et al., Development of a super saturable SEDDS (S-SEDDS) formulation of paclitaxel with improved there solubility that can enhance the bioavability of tell analysis poorlt water soluble drug. Journal of Pharmaceutical Sciences, 2003. 92(12): p. What Is The Function Of The. 2386-2398. 8. Patil Pradeep, R., et al., Bioavailability assessment of tell tale heart ketoprofen incorporated in gelled self-emulsifying formulation to improve the bioavability by using lipid based drug delivery systemAAPS PharmSciTech, 2005. 6(1): p. E9-13. 9. Kang, B.K., et al., Development of self-microemulsifying drug delivery system(SMEDDS) for improve the bioavability by using lipid based drug delivery. Bronte. International Journal of Pharmaceutics, 2004. Tale. 274(1-2): p. 65-73.

10. Palamakula, A. and M.A. Khan, Self-Emulsifying Drug Delivery Systems (SEDDS) for improving bioavability of cytotoxicity of bronte oils used in tale heart, coenzyme Q10. Essay. International Journal of Pharmaceutics, 2004. 273(1-2): p. Tale Heart. 63-73. 11.

Montenegro, L., et al., Effect of oil phase lipophilicity on in vitro drug release from o/w microemulsions with low surfactant content. Drug Development and Essay Industrial Pharmacy, 2006. 32(5): p. 539-548. 12. Attama, A.A. and M.O.

Nkemnele, formulation and evaluation SEDDS using a biodegradable homolipid from Capra hircus. International Journal of Pharmaceutics, 2005. Heart. 304(1-2): p. 4-10. 13. Djordjevic, L., M. Ethical Principles Of Nursing. Primorac, and M. Stupar, In vitro release of diclofenac diethylamide by using a lipid based microemulsion system. International Journal of tale heart Pharmaceutics, 2005. 296(1-2): p. 73-79. 14. Agatonovic-Kustrin, S., et al., Prediction of a Stable Microemulsion Formulation for the Oral Delivery of a Combination of Antitubercular Drugs Using ANN Methodology. Pharmaceutical Research, 2003.

20(11): p. The Multiverse. 1760-1765. 15. Taha, E.I. Response surface methodology for the development and evaluation of tell tale heart analysis self nanoemulsified drug delivery system (SNEDDS) of all-trans-retinol acetate. Pharmaceutical Development and Technology, 2005. 10(3): p. 363-370. 16. Liu, Y., et al., Optimization and in assisi essay, situ intestinal absorption of self-microemulsifying drug delivery system of oridonin for improving bioavability of oridonin. Int.

J. Pharm., 2009. 365: p. 136-142. 17. Tell Heart Analysis. Holm, R., I.H.M. Jensen, and J. Sonnergaard, Optimization of selfmicroemulsifying drug delivery systems using a d-optimal design and the desirability function. The Multiverse. Drug. Dev. Ind.

Pharm., 2006. 32: p. 1025-1032. 18. Tell. Porter, C.J.H., N.L. Trevaskis, and W.N. Charman, Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs. What Is The Function Medulla. Nat. Rev. Tell. Drug Discov., 2007. 6: p. 231-248.

19.Gupta H, Bhandari D and Sharma A. Recent trends in oral drug delivery: a review. Recent Pat Drug Deliv Formul. Bronte Governess. 2009; 3(2): 162-73. 20. de Smidt PC, Campanero MA and Troconiz IF. Tell Analysis. Intestinal absorption of penclomedine from Theory Essay lipid vehicles in analysis, the conscious rat: contribution of emulsification versus digestibility. Security Threats. Int J Pharm.

2004; 270(1-2): 109-18. 21. ODriscoll CM and Griffin BT. Biopharmaceutical challenges associated with drugs with low aqueous solubilitythe potential impact of lipid-based formulations. Adv Drug Deliv Rev. 2008; 60(6): 617-24. 22. Koga K, Kusawake Y, Ito Y, Sugioka N, Shibata N and Takada K. Enhancing mechanism of heart Labrasol on intestinal membrane permeability of the hydrophilic drug gentamicin sulfate. Eur J Pharm Biopharm. 2006; 64(1): 82-91. 23.

Sha X, Yan G, Wu Y, Li J and Fang X. Effect of self-microemulsifying drug delivery systems containing Labrasol on tight junctions in Caco-2 cells. Eur J Pharm Sci. 2005; 24(5): 477-86. 24. Sha XY and principles Fang XL. Effect of self-microemulsifying system on cell tight junctions. Yao Xue Xue Bao. 2006; 41(1): 30-5. 25.

Yang S, Gursoy RN, Lambert G and Benita S. Tale Heart Analysis. Enhanced oral absorption of is the function of the paclitaxel in a novel self-microemulsifying drug delivery system with or without concomitant use of tell P-glycoprotein inhibitors. Pharm Res. The Battle To Beat Cancer Essay. 2004; 21(2): 261-70. 26. Constantinides PP and Wasan KM. Lipid formulation strategies for heart enhancing intestinal transport and absorption of P-glycoprotein (P-gp) substrate drugs: in vitro/in vivo case studies. J Pharm Sci. Ethical Of Nursing. 2007; 96(2): 235-48. 27. Charman WN, Rogge MC, Boddy AW and Berger BM.

Effect of tale food and a monoglyceride emulsion formulation on danazol bioavailability. J. Clin. Pharmacol. 1993; 33: 3816. 28. Threats Essay. Welling PG. Effects of food on drug absorption. Ann. Rev. Nutr. 1996; 16 383415.

29. Araya H, Tomita M and tell Hayashi M. The novel formulation design of O/W microemulsion for improving the gastrointestinal absorption of poorly water soluble compounds. Int J Pharm. 2005; 305(1-2): 61-74. 30. Threats. Shafiq S, Shakeel F, Talegaonkar S, Ahmad FJ, Khar RK and Ali M. Development and bioavailability assessment of ramipril nanoemulsion formulation. Eur J Pharm Biopharm. 2007; 66(2): 227-43. 31.

Palin KJ, Phillips AJ and Ning A. Heart. The oral absorption of principles of nursing cefoxitin from oil and emulsion vehicles in rats. Int J Pharm. 1986; 33: 99-104. 32. Aungst BJ, Nguyen N, Rogers NJ, Rowe S, Hussain M, Shum L and tell tale White. Improved oral bioavailability of an HIV protease inhibitor using Gelucire 44/14 and Labrasol vehicles.

SBT Gattefosse 1994; 87: 4954. 33. Bronte Governess. Saritha D, Penjuri SCB, Nagaraju R. Formulation and tell analysis evaluation of self emulsifying drug delivery system (SEDDS) of Indomethacin, International Journal of Theory Essay Research in Pharmacy and tell Science 2014; 4(2): 17-23. 34. Damineni S Penjuri S C B, and Nagaraju R. Function. formulation and evaluation of self emulsifying drug delivery system (SEDDS) of ibuprofen, International Journal of tale heart Pharmaceutical science and research 2014; 5(8): 3511-3519. 35. . Kumar S, Kumar S G, Kumar P, Sharma R. self-Emulsifying Drug Delivery Systems (SEDDS) for Oral Delivery of Lipid Based Formulations, African Journal of Basic Applied Sciences 2012; 4 (1): 07-11. 36. Reddy M S, Reddy N S, Reddy SM. solubility Enhancement of Poorly Water Soluble Drug Efavirenz by Solid Self Emulsifying Drug Delivery Systems, International Journal of Pharma Research Review, 2014; 3(4): 20-28. 37. Amrutkar C, Salunkhe K, Chaudhari S. study on self nano emulsifying drug delivery system of poorly water soluble drug rosuvastatin calcium, World Journal of Pharmaceutical Research 2014; 3(4): 2137-2151.

38. Choudhari S.B., Mahajan N, Bhalerao A V, self Microemulsifying Drug Delivery System for Treatment of Emesis, Asian Journal of Pharmaceutical Technology Innovation 2014; 02(06): 01-10. 38.Gaikwad G, Godbole M, potnos V, Daud A. Formulation and evaluation of self emulcifying drug delivery system of assisi essay orlistat, Americal Journal Of Pharmtech Research 2012; 2 (6): 297-31. 39. Sachan R, Khatri K, Kasture S. B. Self-Eumlsifying Drug Delivery System A Novel Approach for enhancement of Bioavalibility, International Journal of pharmtech Research 2010; 2(3): 1738-1745. 40. Liu Y., Zhang P., Feng N., Zhang X., Wu S., Zhao J. (2009): Optimization and in tale heart, situ intestinal absorption of self-microemulsifying drug delivery system of of nursing oridonin, International Journal of Pharmaceutics, 365: 136-142. 41. Balakrishnan P., Lee B. Tale Analysis. J., Oh D. H., Kim J. O., Hong M. J., Jee J. Theory. P., Kim J. A., Yoo B. K., Woo J. S., Yong C. S., Choi H. G. (2009), Enhanced oral bioavailability of dexibuprofen by tale analysis, a novel solid Self-emulsifying drug delivery system (SEDDS), European Journal of Pharmaceutics and Internet Security Threats Biopharmaceutics, 72: 539-545. 42. Tale Heart Analysis. Singh A. K., Chaurasiya A., Awasthi A., Mishra G., Asati D., Khar R. K., Mukherjee R. (2009), Oral Bioavailability Enhancement of Exemestane from Self-Microemulsifying Drug Delivery System (SMEDDS), AAPS PharmSciTech, 10(3): 906-916.

43. .Shaji J., Lodha S. (2008), Response surface methodology for the optimization of celecoxib self- emulsifying drug delivery system, Indian Journal of Pharmaceutical Sciences, 70(5): 585-590. 44. Atef E., Belmonte A. A. (2008), Formulation and in vitro and in vivo characterization of a phenytoin self-emulsifying drug delivery system (SEDDS), European Journal of Pharmaceutical Sciences, 35: 257-263. 45. Principles. Fatouros D. G., Nielsen F. S., Douroumis D., Hadjileontiadis L. J., Mullertz A. (2008), In vitroin vivo correlations of self-emulsifying drug delivery systems combining the tell tale analysis dynamic lipolysis model and neuro-fuzzy networks, European Journal of Pharmaceutics and Biopharmaceutics, 69: 887-898. 46. Threats. Shikov A., Pozharitskaya O., Karlina M., Makarov V. (2008), Self-microemulsifying drug delivery system as nanosystems for bioavailability enhancement of flavonoids in vitro, European Journal of Pharmaceutical Sciences, 34 S: S25S29.

47. Woo J. S., Songb Y. K., Hong J. Y., Lim S. J., Kim C. K. Heart Analysis. (2008), Reduced food-effect and enhanced bioavailability of a self-microemulsifying formulation of itraconazole in governess, healthy volunteers, European Journal of Pharmaceutical Sciences, 33: 159-165. 48. Mandawgade S. Tale Heart Analysis. D., Sharma S., Pathak S., Patravale V. B. (2008), Development of SMEDDS using natural lipophile: Application to i??i??-Artemether delivery, International Journal of Pharmaceutics, 362: 179-183. 49. Yi T., Wan J., Xu H., Yang X. (2008), Controlled poorly soluble drug release from solid self-microemulsifying formulations with high viscosity hydroxypropylmethylcellulose, European Journal of Pharmaceutical Sciences, 34: 274-280.

50. . Yi T., Wan J., Xu H. Yang X. (2008), A new solid self-microemulsifying formulation prepared by spray-drying to improve the oral bioavailability of poorly water soluble drugs, European Journal of Pharmaceutics and Biopharmaceutics, 70: 439-444. 51. Abdalla A., Klein S., Mi??i??der K. (2008), A new self-emulsifying drug delivery system (SEDDS) for poorly soluble drugs: Characterization, dissolution, in Threats Essay, vitro digestion and incorporation into solid pellets, European Journal of Pharmaceutical Sciences, 35: 457-464. 52. Tell Tale Heart. Lu J. The Multiverse. L., Wang J. C., Zhao S. X., Liu X. Y., Zhao H., Zhang X., Zhou S. F., Zhang Q. Heart. (2008), Self-microemulsifying drug delivery system (SMEDDS) improves anticancer effect of oral 9-nitrocamptothecin on human cancer xenografts in nude mice, European Journal of Theory Pharmaceutics and Biopharmaceutics, 69: 899-907.

53. Thakkar H., Nangesh J., Parmar M., Patel D. (2011), Formulation and heart characterization of lipid based drug delivery system of raloxifene microemulsion and self microemulsifying drug delivery system, Journal of Pharmacy and Bioallied Sciences, 3(3): 442-448. 54. Cirri M., Muraa P., Mora P. Is The Function. C. (2007), Liquid spray formulations of xibornol by using self-microemulsifying drug delivery systems, International Journal of Pharmaceutics, 340: 84-91. 55. Patil P., Joshi P., Paradkar A. (2004), Effect of Formulation Variables on Preparation and Evaluation of Gelled Self-emulsifying Drug Delivery System (SEDDS) of Ketoprofen, AAPS PharmSciTech, 5(3) Article 42: 1-8. 56. Patel A. Tale Analysis. R., Vavia P. R. (2007), Preparation and In Vivo Evaluation of SMEDDS (Self-Microemulsifying Drug Delivery System) Containing Fenofibrate, The AAPS Journal, 9(3), Article 41: E344-E352. 57. Shen H., Zhong M. Threats. (2006), Preparation and evaluation of self-microemulsifying drug delivery systems (SMEDDS) containing atorvastatin, J Pharm Pharmacol., 58(9): 1183-1191. 58.

Boonme P., Krauel K., Graf A., Rades T., Junyaprasert V. B. Tale Analysis. (2006), Characterization of Microemulsion Structures in the Pseudoternary Phase Diagram of what is the of the Isopropyl Palmitate/Water/Brij 97:1-Butanol, AAPS PharmSciTech, 7(2) Article 45: E1-E6. 59. Agarwal V., Siddiqui A., Ali H., Nazzal S. (2006), Dissolution and powder flow characterization of solid self-emulsified drug delivery system (SEDDS), International Journal of Pharmaceutics, 366: 44-52. 60. Wu W., Wang Y., Que L. (2006), Enhanced bioavailability of silymarin by tell, self-microemulsifying drug delivery system, European Journal of Pharmaceutics and Biopharmaceutics, 63: 288-294.

61. Itoa Y., Kusawake T., Ishida M., Tawa R., Shibata N., Takada K. (2005), Oral solid gentamicin preparation using emulsifier and adsorbent, Journal of Controlled Release, 105: 23-31. 62. Sha X., Yan G., Wu Y., Li J., Fang X. (2005), Effect of self-microemulsifying drug delivery systems containing Labrasol on tight junctions in Caco-2 cells, European Journal of Pharmaceutical Sciences, 24: 477-486. 63.

Subramanian N., Ray S., Ghosal S. K., Bhadra R., Moulik S. P. (2004), Formulation Design of Self-Microemulsifying Drug Delivery Systems for Improved Oral Bioavailability of Celecoxib, Biol. Bronte Governess. Pharm. Bull., 27(12): 1993-1999. 64. Kang B. K., Lee J. S., Chon S. K., Jeong S. Y., Yuk S. H., Khang G, Lee H. B., Cho S. H. (2004), Development of self-microemulsifying drug delivery systems (SMEDDS) for oral bioavailability enhancement of simvastatin in beagle dogs, International Journal of Pharmaceutics, 274: 65-73. 65. Patil P., Joshi P., Paradkar A. Tell Tale Analysis. (2004), Effect of Formulation Variables on Preparation and assisi essay Evaluation of Gelled Self-emulsifying Drug Delivery System (SEDDS) of Ketoprofen, AAPS PharmSciTech, 5(3) Article 42: 1-8. 66. Holm R., Christopher J. H. P., Glenn A. E., Anette M., Henning G. K. , Charman W. N. (2003), Examination of oral absorption and lymphatic transport of halofantrine in a triple-cannulated canine model after administration in self-microemulsifying drug delivery systems (SMEDDS) containing structured triglycerides, European Journal of Pharmaceutical Sciences, 20: 91-97. 67. Itoh K., Tozuka Y., Oguchi T., Yamamoto K. (2002), Improvement of physicochemical properties of N-4472 part I formulation design by using self-microemulsifying system, International Journal of Pharmaceutics, 238: 153-160.

68. Agarwal V., Siddiqui A., Ali H., Nazzal S. (2000), Dissolution and powder flow characterization of solid self-emulsified drug delivery system (SEDDS), International Journal of Pharmaceutics, 366: 44-52. 69. Kim H. J., Yoon K. Tell Heart Analysis. A., Hahn M., Park E. S., Chi S. C., (2000), Preparation and in vitro evaluation of to Beat self-microemulsifying drug delivery systems containing idebenone, Drug Dev Ind Pharm., 26(5): 523-529. 70. Chen G. L., Lee F. Y. (1996), Validation of tell botanical method for Verapamil by high performance liquid chromatography, J Med Sci, 17(1): 16-23. 71.

Shah N.H., Carvajal M.T., Patel C.I., Infeld M.H., Malick A.W. (1994), Self-emulsifying drug delivery systems (SEDDS) with polyglycolyzed glycerides for improving in vitro dissolution and is the medulla oral absorption of tell tale lipophilic drugs, International Journal of Pharmaceutics, 106: 15-23. 74. Indian pharmacopeia. 75. British pharmacopeia. 76. Bhagwat durgachara, D. souza I. development of self micro emulsifying drug delivery inhance dissolution rate of telmisartain, IJDDR 2012,02(04);398-407. 77. Gaikwad G, Godbole M, potnos V, Daud A. Formulation and evaluation of self emulcifying drug delivery system of Theory orlistat, Americal Journal Of Pharmtech Research 2012; 2 (6): 297-31. Search our thousands of essays:

If this essay isn't quite what you're looking for, why not order your own custom Health essay, dissertation or piece of coursework that answers your exact question? There are UK writers just like me on hand, waiting to tell heart analysis help you. Each of us is qualified to ethical principles a high level in our area of expertise, and we can write you a fully researched, fully referenced complete original answer to your essay question. Just complete our simple order form and you could have your customised Health work in your email box, in as little as 3 hours. This Health essay was submitted to us by a student in order to help you with your studies. This page has approximately words. If you use part of this page in tell analysis, your own work, you need to provide a citation, as follows:

Essay UK, Essay: Oral administration of drugs . Available from: [06-10-17]. If you are the original author of this content and no longer wish to Theory Essay have it published on our website then please click on the link below to request removal: 11-08-17 - Smoking habits of university students - CARDIOVASCULAR GENE TRANSFER EFFICIENCY 01-08-17 - Effects of heart analysis stress and anxiety-related disorders on the brain - Autism Spectrum Disorder (ASD) 09-07-17 - Enzyme instructed self-assembly (EISA) 28-05-17 - Glaucoma, Diabetes mellitus and Intra ocular pressure 23-05-17 - Seven functions of what function of the medulla self-injury 18-05-17 - Neurodegenerative diseases 14-05-17 - Warafin genotyping in patients 04-05-17 - Acute lymphoblastic leukaemia. We offer professional custom essay writing, dissertation writing and coursework writing service. Our work is tale heart analysis high quality, plagiarism-free and Internet Essay delivered on time. Essay UK is heart a trading name of Student Academic Services Limited , a company registered in England and Wales under Company Number 08866484 .

Order Essay Services & Assignment Papers Online - "The Tell-Tale Heart" - Cliffs Notes

Nov 17, 2017 Tell tale heart analysis,

Buy Essay Online For Cheap - A literary analysis of a tell tale heart by edgar allan poe

Free Essays on analysis Love In L A By Dagoberto Gilb. ?Ifeanyi Nwagbologu February 3, 2014 English 1102-402 Analytic Writing White Lies in L.A. Dagoberto Gilbs short story, deceiving titled Love in L.A., paints a portrait of a hilarious event involving a minor car accident on the jam-packed Los Angeles freeway. Assisi Essay? When first reading the title, you automatically. Love in L.A. Abstract Traditional love stories have honest, generous, and sometimes wealthy men who show up on white horses to sweep women off their feet.

These stories demonstrate how two strangers can meet unexpectedly, fall in love and tale live happily ever after. Most romantic associations these. Analysis of Love in L.A. Essay? The most intriguing aspect of Dagoberto Gilbs story Love in L.A. is how realistic it really is. Tell Heart Analysis? Generally, love stories follow the traditional pattern of two strangers meeting, falling in love and living happily ever after. Love in L.A by assisi essay, no means follows this. A Love in tell tale analysis, La and Good Man Hard to governess, Find. the jack and grandmother were kind of same sense of tale analysis selfness.

The both character think only for them self and want all the intension towards them. Love in L.A, a story of the person whose name is jack and seems like he is very lazy and disappointed from his lifestyle, wants to get some change in his. Jalisa Torres ENG 102 Libatore Love Has No Existence Here After reading the two short stories, Love in L.A by Dagoberto Gilb and Breast What We Talk about When We Talk about Love by Raymond Carver, I have realized that a common feeling like love can be painted into so many different pictures. Each one of. Colored Plants My Landladys Yard by tale heart analysis, Dagoberto Gilb first published in Internet Security Threats Essay, the Texas Observer, an American political newsmagazine based out of Austin Texas, finds surprising meaning in the futility of yard work. Through out the essay Gilb uses metaphors of his law to explain the racial tensions of immigrants. Last Duchess, ( L .1) in which the tell tale heart Dukes talks of the paintings beauty, Looking as if she were alive.( L .2) Displaying the fact that he actually did find her beautiful. But the Duke goes onto to reveal her faults unto the comrade, saying She looked on, and Theory Essay her looks went everywhere.( L .24) meaning she. ? In Digging the speakers attitudes toward his father are admiration, love , and disapproval. In ll.

1-6 the tell analysis speaker talks in the present tense and describes with admiration what his father is what function of the medulla doing. Snug as a gun in l . Tell Tale? 2 suggests that the bronte speaker is well suited as a writer because the pen fits. only concerned about her and tell heart analysis what she wanted. The Love in L.A story centered around Jake and Mariana where Jake was really only concerned about ethical of nursing himself. The one thing that I found in common was that both stories involved car accidents. Characters: Love in L.A; Jake was the kind of man that causes girls. Time and Fate in Romeo and Juliet Romeo and Juliet, said to be one of the most famous love stories of all times, is tell heart analysis a play anchored on time and fate. Some actions are believed to occur by chance or by destiny. The timing of each action influences the outcome of the play. While some events are of.

A Strong Liaison Sportd by The Multiverse Theory Essay, Brutus. early portions of the analysis play, Brutus tells Cassius, What means this shouting? I do fear the The Battle Breast Cancer people do choose Caesar for their kingyet I love him well (A.I, sc.ii, l .86-90). Brutus cares for Caesar but refuses to allow Caesar to gain command, to tale heart analysis, turn his back to the people of Rome, to domineer Rome. Love in L.A. and M Is for Moon Among Other Things. For Jake and Alfred, the male characters from Love in L.A. and M is for Moon Among Other Things, respectively, reality is far from their perception of the medulla good life. Both men dream of living quite differently from the heart one they have been leading, yet neither deserve what they desire. Jake and Alfred. Brief Information for Major American Authors of the governess Romanticism Period in Britain.

greatest British poets and remains widely read and influential. Byron was celebrated in tale heart, life for aristocratic excesses, including huge debts, numerous love affairs. He travelled to fight against the Ottoman Empire in the Greek War of Independence, for which Greeks revere him as a national hero.[1] He died. Psychosexual stages 11. Childhood stage of development i. Oral j. Anal k. Phallic l . Latency m. Genital ii.

Pleasure seeking energies focus on erogenous zones ix. Oedipus-complex . Uncle Rock The Story Uncle Rock by Dagoberto Gilb is about a look inside the life of a young eleven year old boy named Erick who uses his actions to show his disapproval of the countless men that come in Breast Essay, and out of his beautiful mothers life. After watching numerous relationships fail, Eric finally. community deal with the ever-growing problem of materialism. It is instead an tell, illustration of how one woman dealt with the conflict of her love for her possessions and The Battle to Beat Breast Cancer Essay her love for her God.

For example, in a poem titled Here Follow Some Verses Upon The Burning Of Our House July 10, 1666, Bradstreet chronicles. pass ( l . 4); large gaps in the wall where two people could pass through side by side. Frozen tree roots push up the tell ground and create gaps. The narrator is wondering if the tree is assisi essay following along with his thoughts and does not want the wall there also: Something there is that doesnt love a wall. even feel myself. I was as autumn leaf the tell wind takes from one place to another. What Function Of The Medulla? I felt lost. I had been with L for two and a half years now. We were deeply in love . He was the only reason for me to be alive. When I loved him, I loved him deeply and gave to him all of me. I thought only.

person. Heart? (Boone, L.E. Kurtz, D. L .; 2012). They have a new hire process that they take seriously so that no sells will be left out. They want to make sure that their staff is principles with people who come to tell analysis, work every day and is the function of the medulla believe in what they are selling. Tale Heart? (Boone, L.E. Kurtz, D. L .; 2012). Thats why they believe. True Love Facing Separation in John Donne's A Valediction Forbidding Mourning.

True love facing separation in bronte governess, John Donnes A Valediction: Forbidding Mourning Before getting into detail concerning the topic of true love in tell heart analysis, combination with separation Id like to give a short overview for how I have understood the is the function of the content and action in tell tale analysis, John Donnes poem. June 1, 2011 Love in L.A. by Dagoberto Gilb Selfish, deceitful people exist throughout America. Yet, from reading the short story Love in L.A. the assisi essay rest of tale heart America would probably view the way the city promotes its lifestyle as disoriented. The story is centered on what is the medulla a man born a raised in the. them together. Beatrice confirms this when she mumbles under her breath you always end with a jades trick; I know you of old to Benedick (A1 SC.2 L .142) By having past experiance with each other, Benedick and Beatrice can know if they are truly compatible with each other. Hero and tell tale heart analysis Claudio on the other.

LOVE L is for the way you look at me O is for the only one I see V is very very extraordinary E is even more than anyone that you adore Assalamualaikum and a very good morning to our beloved English teacher and assisi essay members of the floor. My name is . and I would like to talk. Driving Dagoberto Gilbs Love in L.A. is a love story that is set on a freeway in Las Angeles. Now this is an unusual setting for a love story, however, Love in L.A. is a different kind of tell analysis love story. Essay? The story opens up with Jake, a careless and analysis irresponsible guy sitting in The Battle, traffic. Gilb states. A Thing Called Love The difference between two separate opinions of love could be very similar, yet could be drastically contrasting. In the story Love in L.A., written by Dagoberto Gilb , Jake has, what would appear to tell analysis, a normal person, a skewed vision of love . Out of everything in his world. Introduction SIR THOMAS WYATT (?15O3-1542) xxv 3 4 5 6 7 8 9 10 11 12 13 14 15 1. 'Whoso list to hunt, I know where is an hind' 2. 'Farewell, love , and all thy laws for ever' 3. 'Unstable dream, according to the place' HENRY HOWARD, EARL OF SURREY (?1517-1547) 4. Medulla? 'Set me whereas the sun doth. Journal Entry #1 Love in tell, L.A. by Dagoberto Gilb.

#1 Love in Essay, L.A. by Dagoberto Gilb p. 311 Word count: 522 Summary Love in tale heart, L.A. is a story that is set on the streets of Los Angeles in the heat of traffic. Love should be an emotion of strong affection and personal attachment (DK). But in the short story Love in L.A., the definition of love is. ?Analysis of George Bushs the mission goes on speech. informing his people. Bronte? He wants them to stay steadfast and tell tale heart analysis calm. Moreover he wants to represent his country in a good way by mentioning its gratness ( l .10 f.). The message in Internet Essay, the speech is that the Americans are strong and know how to handle with situations like this. Regarding to the headline, this kind. In Dagoberto Gilbs story Al in Phoenix the narrator feels that Al is treating him unfairly. The narrator believes that Al thinks of him as a guy that is tell heart analysis living loose and not bothering to get a job ( Gilb 75-81).

The narrator being the Security Threats inductive thinker thought that Al was being unfair to him because. The Effects Divorce Has on tell tale analysis Children. that if you get pregnant, you have to get married. We now have teenagers getting married before they are 20 years of age to someone they think they love because they made a baby with that person. That couple then brings that baby into the world and a lot of the time the marriages are not working anymore. Pfeffer's last two dimensions relate to membership. Vision where the Theory Essay group is going and why they should want to go there. Heart? Altruistic love unconditional, unselfish, unlimited care and concern for bronte others and for tell heart analysis self. Results include joy, peace, and serenity. Hope/faith hope that. bastard shame ( l . Essay? 4). Regardless of a womans physical attractiveness, Shakespeare contends that the use of make-up constitutes an act of insincerity and dishonesty, as the made-up face is tell heart analysis a false borrowed face ( l . 6) that is disgraceful.

Even for governess the woman who is not born fair ( l . 11), making oneself. SAFASFSFASFSAFAF DDSFDSA FSADF SADS. from a religious point of view and therefore condemning it. Others have taken a similar approach to support it and every humans right to choose who to love or not. Other argue against it based on nature, however, whichever approach those against the practice use to condemn it, those in support of this sexual. shared experiences, activities, exchange of ideas, views, and tale analysis gossip and finally, friends meet social-emotional needs by providing love and esteem (Lenton, A.P. and Webber, L ., 2006). As friendships of the assisi essay same-sex allow a relatable source which emotions and tell tale heart analysis convictions can be relayed to, the opposite. Compassionate Love as a Cornerstone. J Bus Ethics (2015) 128:119131 DOI 10.1007/s10551-014-2085-z Compassionate Love as a Cornerstone of Servant Leadership: An Integration of bronte governess Previous Theorizing and tell heart Research Dirk van Dierendonck Kathleen Patterson Received: 2 December 2012 / Accepted: 29 January 2014 / Published online: 13 February.

same rhyming element (qafiyeh) Standard outline of qasidah Three main thematic divisions Love prelude: the nasib, or amatory prelude; characterised by the poets melancholic nostalgia for a past love affair. Such nostalgia is Internet Security Essay usually prompted by his encountering and describing the traces of his. Euthanasia and tell heart analysis End-of-Life Decisions. wills take away a lot of hard end of life decisions that many families are left to make about their love one. Often times these families are too wrapped up in their emotions to stop and think what their love one would have wanted when they are making these decisions. Technology complicates the assisi essay dying process. Love in L.A.

The story Love in tell heart, L.A. is a short story written by Dagoberto Gilb in 1986. It is a love story based on realistic approaches. One of the main characters was Jake, who was dreaming while driving. Security Essay? However, this caused an tell tale, accident; he crashed into bronte governess a Toyota that was in front of him. Mariana. grew up in different places. As I am a single parent family, grew up without a mother, but my father to live with his love to make up for the shortcomings of my lack of maternal love . Although I am the only child at home, but I am very independent, thinking the same age than the average person mature. things rank and gross in nature Possess it merely. ( l . 129 - 137) The world in Hamlets view, or at least that part of it represented by analysis, Elsinore and Denmark, is a place of The Battle to Beat Cancer Essay deception and decay. Hamlet is, or until recently has been, in love with Ophelia. This is tell tale heart analysis arguably the only positive in Hamlets.

l What is proper love ? Is it intelligent love , and does Austen understand love in Theory, the fullest sense, as Lionel Trilling suggests? If so, do her protagonists naturally have the tell heart analysis ability to love intelligently, or do they develop it? What qualities and behavior lead to a happy marriage Marriage. venture, had a mind so crude any idea could violate it. Bronte? And yet who could not somehow honor his wooden conceits as well as lumpish sentences? Not H. L . Mencken, who both loved them and loved to tell analysis, lambast them.

Not even my students (though all were relieved to move on with the syllabus). Of course, off. Love is a powerful force that drives one person to draw a deep affection towards another. When analyzed, the short story entitled Love in L.A., by Dagoberto Gilb , shows how one can see many reasons in seeing irony and even satire by the story's title. Through Jake, the protagonist's definition of. Why I Choose Washington and Lee University. Why I choose Washington Lee and what I will contribute to The Battle Breast Cancer, the W L community. My timetable for tale heart a normal day in the W L campus: 7 a.m: Get up. Take a deep breath. Open the window to enjoy the beautiful glow of Lexingtons dawn.

7.30 a.m: Go to the gym. Work out. Then take a shower. 8.30 a. Putting Unity in Its Place: Organic Unity in Cancer Essay, Platos Phaedrus. the Phaedrus itself.3 I At the end of tell tale Lysias speech, Phaedrus enthusiasm for it is evident.

Literature Aesthetics 19 (1) June 2009, page 153 L A 2009.1.indd 153 9/9/09 8:49:45 AM Putting Unity in Its Place: Organic Unity in Platos Phaedrus Visibly lit up by Theory Essay, the speech, he calls it. La Love and Good Man Hard To Find. The story A GOOD MAN IS HARD TO FIND and LOVE IN L.A are set in different time periods but have a common ground both stories mention a setting of being in the summer at heart, one point of time also both stories have a similar setting which took place on a highway. There are many differences in The Multiverse Theory Essay, both stories. Literature, Love in La, a Good Man Is Hard to Find. Love in L.A. by Dagoberto Gilb The setting of this short story is on the freeway of heart analysis Los Angeles. Jake is a self-absorbed, lazy, irresponsible, protagonist, who is driving along the freeway.

He begins daydreaming about of nursing a car better than his 58 Buick, with crushed velvet interior and tell heart an FM radio. | MAGNUM OPUS FORMATION SCHOOL | Padre Garcia, Batangas | 043-515-8998 | 5 July 2011 Dear parents/guardians, Greetings of peace and love ! Our school, Magnum Opus Formation School aims to hone its pupils in their academics and values formation. It is the primary goal of each and every. ? Portfolio Assignment: Popular Music Analysis Anita L . Levy Remington College OGE3540-QRT February 2, 2014 Portfolio Assignment: Popular Music Analysis According to Mark 10:6-9, But from the beginning of creation, God made them male and female. Therefore a man shall leave. Edith L . Essay? Tiempo (Edith Lopez Tiempo) b. Bayombong, Nueva Vizcaya 22 Apr 1919. Poet, fictionist. She is the daughter of Salvador T. Lopez and tell analysis Teresa Cutaran. Her childhood was spent in various Philippine provinces where her father was assigned as a government auditor. She graduated from high school.

vacation, or driving through the busy streets of Hollywood, traffic on the highways and streets of Los Angeles can often be a hassle. In Dagoberto Gilb's short story Love in L.A., first published in 1986, the troubles of traffic are experienced first hand by our main character Jake. Jake is a common fellow. hour a day with his son, but then its back to work until he finally goes to Essay, bed around midnight. Says Clark, There are plenty of people who would love to tell heart analysis, have this job. Theyre knocking on the door all the time. So thats motivating. Many individuals would balk at the prospect of a 60-hour or. care is vital in order for bronte governess this model to be effective and successful. Healing hospitals go way beyond just being a building. Its strong culture of love and caring is what sets it apart from traditional hospitals (Chapman, 2010, p. 15). Components of the healing hospital There are three components.

parodies are love and tell tale heart analysis knighthood. Topaz falls in love with an elf queen, which is nowhere near a real relationship. He lives in a fantasy. The Battle To Beat Essay? He has not met the elf queen but he states that he is in love . All other woman I forsake, for to an elf queen Ill betake, in dale and over down! ( L : 794-796). . Pablo Neruda Love is like a garden; it grows, it dies, it sprouts anew. In Pablo Nerudas book, Twenty Love Poems and a Song of Despair, he writes intricate poems about the lust and loss of love . Heart Analysis? Even though he was only in his 20s in 1924, he knew what he was talking about.

At the age that I am. Love is a powerful force that drives one person to draw a deep affection towards another. When analyzed, the short story entitled Love in assisi essay, L.A., by Dagoberto Gilb , shows how one can see many reasons in seeing irony and even satire by the story's title. Through Jake, the protagonist's definition of. received an email that asked the question What is Love ?. The answers were from a group of children ages four to six years old. Tell Tale Analysis? Their minds amazed me. Some of the answers were funny, Love is when mommy gives daddy the best piece of is the function fried chicken or Love is when mommy sees daddy on the toilet and she. up in a scandalous affair. I do love you I said more than ever: but I must not show or indulge the tell heart feeling and this is the last time I must express it.(Bronte 266).

But Jane refuses to give up her self-respect by becoming a rich man's mistress, even though she loves him still. In Jane. Are you ready to tolerate my presence daily? Why do people more often refuse from The Battle to Beat Breast Cancer Essay official confirmation of heart analysis their love , honey? The reason may be in juveniles lack of knowledge in Threats, the issue of marriage and family.

Therefore, entry into marriage is often unconscious.